IMMUNODEFICIENCY
Clinical trials for IMMUNODEFICIENCY explained in plain language.
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Radical transplant trial offers hope for devastating new disease
Disease control Recruiting nowThis study is testing whether a stem cell transplant from a donor can control VEXAS syndrome, a serious and often treatment-resistant disease that causes severe inflammation and blood problems. Researchers will give 54 adults with severe VEXAS a transplant after using medications…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New hope for vulnerable patients: study tests stronger COVID treatments
Disease control Recruiting nowThis study aims to find better COVID-19 treatments for people with weakened immune systems. Researchers are testing whether combining two antiviral drugs works better than using one alone, and whether extending treatment from 5 to 10 days helps clear the virus faster. The trial w…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: Calmy Alexandra • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Scientists test Double-Duty drug combo to knock out COVID in vulnerable patients
Disease control Recruiting nowThis study is testing if using two antiviral drugs together works better than one alone, and if taking the main drug for 10 days is better than 5 days, for people with weakened immune systems who get COVID-19. It aims to help these high-risk patients clear the virus faster and mo…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for rare immune disorder: can a transplant reset the Body's defenses?
Disease control Recruiting nowThis study is testing whether a stem cell transplant from a matched donor can treat GATA2 deficiency, a rare genetic disorder that causes serious infections and can lead to blood cancers. The transplant aims to replace the patient's faulty bone marrow with healthy donor cells to …
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Hunting the genetic roots of rare immune diseases
Knowledge-focused Recruiting nowThis study aims to discover the specific genes that cause certain inherited immune disorders and understand how they affect health and family risk. It involves patients and their family members who have or are suspected of having these genetic conditions. Participants provide blo…
Matched conditions: IMMUNODEFICIENCY
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Parkinson's drug under scrutiny: could it weaken your defenses?
Knowledge-focused Recruiting nowThis study aims to understand if the Parkinson's psychosis medication clozapine affects the body's immune system over time. Researchers will follow 24 Parkinson's patients taking clozapine, measuring their antibody levels and immune cells at 6 months and 1 year. The goal is to ga…
Matched conditions: IMMUNODEFICIENCY
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC