Immune-Guided drug timing could cut CMV prevention after transplant
NCT ID NCT07569653
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a personalized approach to stopping the drug Letermovir, which prevents a common virus called CMV after a stem cell transplant. Instead of giving the drug for a fixed 100 days, doctors will use a blood test to see when a patient's own immune system has recovered enough to fight CMV. The goal is to see if this strategy can safely reduce how long the drug is needed, lowering costs and side effects. The study involves 120 adult transplant recipients in China.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chinese PLA General Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100853, China
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Henan Cancer Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450008, China
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Jingzhou Central Hospital
NOT_YET_RECRUITINGJingzhou, Hubei, 434020, China
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Jingzhou First People's Hospital
NOT_YET_RECRUITINGJingzhou, Hubei, 434000, China
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The Affiliated Hospital of Inner Mongolia Medical University
NOT_YET_RECRUITINGHohhot, Inner Mongolia, 010050, China
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The First Affiliated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, Jiangxi, 330006, China
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The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITINGWenzhou, Zhejiang, 325000, China
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The First Affiliated Hospital of Zhengzhou University
NOT_YET_RECRUITINGZhengzhou, Henan, 450052, China
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The Second Hospital of Hebei Medical University
NOT_YET_RECRUITINGShijiazhuang, Hebei, 050000, China
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITINGWuhan, Hubei, 430030, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430022, China
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Zhongnan Hospital of Wuhan University
NOT_YET_RECRUITINGWuhan, Hubei, 430071, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can immune cells predict herpesvirus danger in transplant patients?
- Can gut bacteria help rebuild immunity after stem cell transplants?
- Can specially grown immune cells from donors beat viruses that won't go away?
- Can a safer dose of an old drug shield vulnerable children from deadly fungal infections?
- Immune cell levels may predict who will develop severe CMV after transplant
- Could virtual reality help patients recover faster from cell therapy?