GLIOBLASTOMA MULTIFORME

This study looked at whether a modified Atkins-based diet with short-term fasting is possible for people with glioblastoma, a serious brain cancer. Twenty-five patients who had already completed standard treatments tried the diet for 8 weeks. The goal was to see if they could sti…

This early-phase study tested whether adding the drug chlorpromazine (normally used for other conditions) to standard chemotherapy and radiation is safe for people newly diagnosed with glioblastoma, an aggressive brain cancer. Ten adults participated to find the best dose and che…

This study tested a drug called VAL-083 combined with standard radiation for people newly diagnosed with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). The goal was to find a safe dose and see if the combination helps control th…

This small pilot study tested a device called NaviFUS that uses focused ultrasound waves, combined with the standard drug bevacizumab, in 6 adults whose glioblastoma brain tumor had returned after prior treatment. The goal was to see if the combination was safe and could help con…

This study looked at whether giving a second round of radiation is safe for people whose glioblastoma (a fast-growing brain tumor) has come back after standard treatment. Seventeen adults aged 18 to 50 with good overall health took part. The goal was to find the highest safe dose…

This study tested a device called Optune that creates electric fields to disrupt cancer cell growth. It was given alongside standard radiation and chemotherapy to 981 adults with newly diagnosed glioblastoma, an aggressive brain cancer. The goal was to see if adding Optune helps …

This early-phase study tested a new drug called tinostamustine in 10 people with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (unmethylated MGMT). Participants received the drug after standard treatment to see if it is safe and how the body proces…

This early-stage trial tested an experimental drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had returned or worsened after standard treatment. The main goals were to find a safe dose and understand how the drug behaves in the body. The dru…

This study looked at 33 adults with glioblastoma, a fast-growing brain cancer, whose tumors worsened soon after surgery. Researchers used a special PET scan with 11C-methionine to see tumor activity better than standard MRI. The goal was to adjust radiation therapy plans based on…

This study tested whether a special type of scan (FET-PET/MRI) can more accurately map the full extent of glioblastoma brain tumors after surgery compared to standard MRI. The goal was to see if this could help doctors plan radiation treatment more precisely, potentially improvin…