New hope for kids with tough brain cancers? early trial tests INCB7839
NCT ID NCT04295759
First seen Jan 07, 2026 · Last updated Apr 30, 2026 · Updated 19 times
Summary
This early-phase study tested a drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had come back or worsened after standard treatment. The main goal was to find a safe dose and check for side effects. The drug works by blocking a protein that helps tumors grow, aiming to slow or stop the cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60614, United States
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Children Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90026, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cincinnati Children Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02245, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Stanford University and Lucile Packard Children's Hospital
Palo Alto, California, 94304, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.