GASTROINTESTINAL CANCER

This trial tested a new treatment for people with advanced gastrointestinal cancers (like stomach, colon, or pancreatic cancer) that had spread and stopped responding to standard therapy. Doctors took immune cells from each patient's tumor, used CRISPR gene editing to remove a ge…

This early-phase study tested a new drug called cabotamig in 33 adults with advanced gastrointestinal cancers (like colon, stomach, liver, or pancreatic cancer) that had stopped responding to standard treatments. The drug works by attaching to a marker on cancer cells and helping…

This early-phase trial tested a new treatment for people with advanced cancers (like pancreatic, stomach, or colon cancer) that have a specific genetic change called KRAS G12D. Doctors took participants' own white blood cells, modified them in a lab to better recognize and attack…

This early-stage study tested a new drug (BI 765049) alone or with another drug (ezabenlimab) in 21 Asian adults with advanced solid tumors like lung, stomach, or liver cancer. The goal was to find a safe dose and see if the drugs could shrink tumors. Participants received infusi…

This study tested a new drug (TJ004309) combined with an approved immunotherapy (atezolizumab) in 25 people with advanced ovarian, head and neck, lung, gastrointestinal, or triple-negative breast cancers. The goal was to see if the combination could shrink tumors. Participants ha…

This study tested whether ultrasound can detect nerve damage caused by the chemotherapy drug oxaliplatin in people with gastrointestinal cancer. Twenty participants who had or were receiving oxaliplatin and had nerve symptoms were scanned. The goal was to see if ultrasound could …

This study looked at whether having a palliative care team work alongside surgeons improves the well-being of patients with gastrointestinal cancers (like pancreatic or liver cancer) and their family members. About 379 patients and their companions took part. The goal was to see …

This study tested a program called STRONG-PD that provides nutrition support remotely to people with gastrointestinal cancer that has spread to the lining of the abdomen. Ten participants who had surgery and chemotherapy used the program to track their diet and meet with a dietit…

This study tested whether taking silkworm pupa tablets for 3 months could improve nutrition and reduce frailty in 120 people who had surgery for stomach, colon, or other gastrointestinal cancers. Participants were randomly assigned to receive either the tablets or a very low dose…

This study looked at whether adding oral nutrition supplements to standard chemotherapy helps people with gastrointestinal cancer. 175 adults took part. Researchers measured body composition, nutrition status, and side effects. The goal was to see if supplements improve quality o…

This study tested whether a simple walking program, tracked with fitness trackers, could help people with various cancers (brain, head and neck, lung, gastrointestinal, or cervical) complete their planned chemoradiotherapy without missing treatments. 166 adults who could walk ind…

This study looked at 100 adults having gastrointestinal cancer surgery to see if sarcopenia (muscle loss) changes how muscle relaxants work during anesthesia. Researchers used CT scans to group patients as sarcopenic or not, then measured how fast the drugs worked and how long th…

This study looked at how a common chemotherapy drug called 5-FU affects small blood vessels in cancer patients. Researchers measured blood flow in the skin of 62 people, including current and past 5-FU patients, those on other chemotherapies, and healthy volunteers. The goal was …

This study tested a program called BOLSTER, designed to provide extra support for people with gynecologic or gastrointestinal cancers and their caregivers after a hospital stay. The goal was to see if the program was practical and if participants liked it. 121 patients took part,…

This study looked at whether asking cancer patients to report their own symptoms during radiation treatment helps doctors notice and manage side effects better. 104 adults with lung, esophageal, or other gastrointestinal cancers took part. Doctors reviewed patient-reported sympto…

This study looked at how muscle energy use changes in undernourished patients with gastrointestinal cancer. Researchers measured muscle cell power plants (mitochondria) and fat droplets in 51 patients. The goal was to learn more about cancer-related wasting, which can lower quali…

This study looked at how to best encourage DPYD testing in people with gastrointestinal cancer before they start certain chemotherapy drugs. DPYD testing can show who is at higher risk for severe or even deadly side effects. Researchers tested different messages with 50 participa…