Gene-Edited immune cells take on stomach and colon cancers

NCT ID NCT04426669

First seen Mar 03, 2026 · Last updated Jun 10, 2026 · Updated 17 times

Summary

This trial tested a new treatment for people with advanced gastrointestinal cancers that had spread and stopped responding to standard therapy. Doctors removed immune cells from patients' tumors, used CRISPR gene editing to boost their cancer-fighting ability, and then infused them back. The study involved 23 participants and aimed to find the safest dose and measure tumor shrinkage.

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Contacts and locations

Locations

  • Masonic Cancer Center, University of Minnesota

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.