ESOPHAGEAL CANCER

This study tests a new treatment that uses a radioactive substance (lead-212) to target and destroy cancer cells in people with advanced solid tumors like pancreatic, stomach, and ovarian cancer. The treatment is guided by imaging to ensure it reaches the right cells. The goal is…

This phase 3 trial tests whether adding two drugs—toripalimab (an immunotherapy) and capecitabine (a chemotherapy pill)—after standard chemoradiation can help prevent esophageal cancer from coming back. About 242 adults with advanced esophageal cancer who have not worsened after …

This study tests whether adding personalized integrative care—like naturopathic support, a Mediterranean diet, and exercise—before and after surgery can improve quality of life and reduce complications for people with lung, stomach, or esophageal cancer. About 20 adults scheduled…

This study is testing a new blood test that looks for DNA signals from 20 different cancers, including lung, breast, and colon cancer. Researchers will enroll 7,000 people to see if the test can find cancer early, detect any cancer left after treatment, and spot a relapse before …

This study is for people with certain advanced cancers (like lung, head and neck, or esophageal cancer) who are already receiving immunotherapy. Researchers want to see if adding radiation therapy improves outcomes and if simple blood tests can predict who will benefit most. The …

This study is a large registry that will follow about 8,000 cancer patients who receive radiation therapy using a special machine called an MR-Linac, which combines an MRI scanner with a radiation beam. The goal is to learn how well this technology works for different cancers, in…

This study collects tissue, blood, urine, and stool samples from 5,000 people undergoing colonoscopy or endoscopy, including those with or without cancer. Researchers aim to find new biomarkers that could lead to earlier detection of colorectal, esophageal, gastric, and pancreati…

This study collects tissue and blood samples from people with stomach or esophageal cancer, as well as those at high inherited risk, to learn how genes and proteins contribute to these cancers. The goal is to better understand the disease, not to test a new treatment. About 100 p…