EYE DISEASES

This study tested a new drug called LASN01 in 41 adults with moderate-to-severe thyroid eye disease, a condition that causes eye bulging and discomfort. The drug aims to reduce eye bulging and inflammation by blocking a specific receptor. Participants received either LASN01 or a …

This early-stage study tested the safety of a new medicine called VP-001, given as an injection into the eye, for people with a rare inherited retinal disease caused by a PRPF31 gene mutation. Six participants received multiple doses to see if the treatment was safe and tolerable…

This study tested whether a steroid eye drop (fluorometholone) given twice daily for four weeks after trachoma surgery could prevent eyelashes from growing back and rubbing against the eye. Over 2,400 people aged 15 and older with trachomatous trichiasis took part. The goal was t…

This study tested a new type of artificial lens (PODEYE TORIC) for people having cataract surgery who also have astigmatism, a condition where the eye is shaped like a football instead of a basketball. 261 adults received either the new lens or a standard lens. The goal was to se…

This study tested the long-term safety of an eye drop called LNZ101 for people with presbyopia, a common age-related condition that makes it hard to see things up close. 362 adults aged 45 to 75 took part. The main goal was to see how many had side effects related to the treatmen…

This study tested an eye drop called LNZ101 to improve near vision in people with presbyopia, an age-related condition that makes it hard to see close objects. The trial involved 229 adults aged 45 to 75. The goal was to see if the drops could improve near vision by at least thre…

This phase 3 study tested whether LNZ101 eye drops can safely improve near vision in adults aged 45-75 with presbyopia (age-related blurry close-up vision). 469 participants received the drops and were checked on day one for a three-line or better improvement in reading vision wi…

This study tested a new questionnaire designed to measure how well babies (0-36 months old) with eye diseases can see, even before they can talk. The goal was to see if the questionnaire is accurate and reliable, so doctors can better decide when to perform surgery. 150 children …

This early-phase study at Stanford tested whether an oral nutritional supplement called alpha-ketoglutarate can reach the eyes and affect eye health. Seventeen adults with age-related eye diseases took the supplement before cataract surgery. Researchers measured how much of the s…

This study looked at whether an online eye screening, guided by a nurse, is a good value for older adults (65+) who get home healthcare. The goal was to see if it helps find and reduce eye problems. 234 people took part, and researchers measured changes in vision over time.

This study tested a special eye-imaging technique called adaptive optics to look at blood vessel changes in the retina of people with multiple sclerosis (MS). Researchers measured swelling around retinal vessels in 50 participants with different MS types and compared them to heal…

This study checked if measuring propofol (an anesthesia drug) in children's breath can accurately show how much is in their blood. 32 children having eye surgery took part. Researchers compared breath levels with blood samples and brain activity monitors. The goal was to see if a…

This completed study involved 2,000 people with eye complaints to see if artificial intelligence (AI) can diagnose eye diseases as accurately as eye doctors. Researchers compared the diagnoses and advice from AI language models with those from real ophthalmologists. The goal was …