AI eye exams: chatbots take on ophthalmologists in landmark trial

NCT ID NCT07154680

Completed Diagnosis Sponsor: North Sichuan Medical College Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed trial tested whether large language models (AI chatbots) can diagnose eye diseases like cataracts and glaucoma. Researchers compared the diagnostic accuracy of several AI models against real ophthalmologists using patient complaints and eye images from 2000 participants. The goal was to see if AI could provide reliable medical advice and speed up diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Large language models (AI chatbots) including GPT-4o, Claude, Gemini, and Llama
What this could lead to: If successful, this could show that AI can help diagnose eye diseases quickly and accurately, potentially supporting doctors and improving access to eye care.
What could go wrong: This is a completed study, but AI may not match the accuracy of a human eye doctor, and results may not apply to all types of eye disease or real-world clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

eye disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EYE DISEASES

Contacts and locations

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Locations

Afﬁliated Hospital of North Sichuan Medical College

Nanchong, Sichuan, 637000, China

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