ESSENTIAL HYPERTENSION

This early-stage trial is testing a new drug called KK3910 in healthy people and those with high blood pressure. The main goal is to check safety and how the drug moves through the body. It is a small, placebo-controlled study, so it is too soon to know if the drug actually works…

This study tests a health coaching program called STAR-MAP to help older adults (age 40+) with high blood pressure take their medication regularly. About 402 participants with uncontrolled blood pressure and low medication adherence will be recruited through a Louisiana health in…

This study is testing a new educational tool called the Decreased Salt High Potassium (DSHP) Tool, designed to help adults with high blood pressure reduce their salt intake and eat more potassium-rich foods. About 190 participants from two clinics in Singapore will either receive…

This study tests whether a new combination drug works better than taking two separate medicines for people with both high blood pressure and type 2 diabetes. About 228 adults will take either the combo pill or a single-ingredient pill for 12 weeks. Researchers will check changes …

This study tests if dapagliflozin, a diabetes drug, can reduce heart and blood vessel risks in women who had high blood pressure during pregnancy. About 200 participants will take either the drug or a placebo daily for six months after delivery. The goal is to see if the drug imp…

This study tests whether a mobile health program that helps children sleep longer can lower their blood pressure. Ten children recently diagnosed with essential hypertension who sleep 7.5 hours or less on school nights will use a sleep tracker and receive guidance to extend their…

This study tests if using focused ultrasound to modify fat around the kidney can safely lower blood pressure in people with hypertension. About 30 adults with mild high blood pressure despite medication will be enrolled. The treatment is compared to a sham procedure to see if it …

This study tests whether a telemedicine system (HealthCap app) can keep blood pressure under control as well as regular face-to-face doctor visits in people with stable hypertension. About 364 participants will either use the app for remote monitoring and automatic medication ref…

This phase 3 trial tests whether a combination pill containing sacubitril and valsartan (CKD-202A) works better than valsartan alone for essential hypertension. About 324 adults with high blood pressure will take either the combo or the standard drug for 10 weeks. The main goal i…

This Phase 3 trial tests whether taking dapagliflozin and telmisartan together works better than either drug alone for people with type 2 diabetes and high blood pressure. About 221 adults will receive either the combo or a single drug for 12 weeks. Researchers will measure chang…

This study aims to find genes that cause high blood pressure starting in childhood. Researchers will follow 2,300 people aged 2 and older, including those with childhood-onset hypertension and their healthy relatives, for up to 10 years. Participants provide blood, urine, and che…

This pilot study tests whether a drug called aprepitant (currently used for nausea) can lower a hormone called aldosterone in people with severe sleep apnea and high blood pressure. The study will enroll 24 adults and measure aldosterone levels before and after taking the drug or…

This study is checking whether people newly diagnosed with high blood pressure who also have high homocysteine levels are more likely to have early signs of heart stiffness. Researchers will measure homocysteine in blood and use ultrasound to look at heart function in 500 adults.…

This early-stage study is testing a new drug called BCD101 in 56 healthy adults to see if it is safe and how the body processes it. Participants will receive either the drug or a placebo, and researchers will monitor for side effects and measure drug levels in the blood. This stu…