ESSENTIAL HYPERTENSION

This phase 3 trial tests whether a new drug called HCP1803-4 can safely lower blood pressure in adults with essential hypertension. Participants are randomly assigned to receive either the new drug or a control drug. The study measures changes in sitting blood pressure over time …

This study tests a non-invasive device that uses gentle electrical stimulation on the brain to see if it can safely lower blood pressure in people with mild hypertension. Sixty adults aged 30-65 with mild high blood pressure will receive either real or sham stimulation for 20 min…

This study tests whether a device that temporarily restricts blood flow to the arms (remote ischemic conditioning) can help lower blood pressure in people with hypertension who moved to high-altitude areas. 184 adults will either continue their usual medication or add the device …

This study tests a 12-week program that combines a healthy diet, exercise, sleep, and stress management with a careful plan to reduce blood pressure medication. The goal is to see if people with high blood pressure can stop taking their pills and keep their blood pressure normal.…

This early-stage trial is testing a new pill called BR1015-A, which combines two common blood pressure medicines (fimasartan and indapamide) into one tablet. The study will involve 58 healthy adult volunteers to see how the body absorbs and processes the drug, and to check for an…

This early-stage trial tests a new combination pill (BR1015-A) containing two blood pressure medicines, Fimasartan and Indapamide, in 58 healthy adults. The goal is to see how the body absorbs and processes the drugs and to check for any safety issues. Participants will take the …

This early-stage trial will test a new combination pill containing two blood pressure medicines (fimasartan and indapamide) in 48 healthy adults. The study compares the combined pill to taking each drug separately, measuring how the body absorbs the drugs and checking for side ef…

This phase 2 trial tests five different doses of an experimental drug called BR1400 in 330 adults with essential hypertension (high blood pressure). Participants take one tablet daily for 8 weeks to see how well it lowers blood pressure and if it is safe. The study compares the d…

This study tests a new medicine called BEBT-701, given as a shot under the skin, for people with mild to moderate high blood pressure and high LDL cholesterol. The goal is to see if it is safe and can help lower both blood pressure and cholesterol. About 340 adults aged 18 to 60 …

This early study tests a device that targets specific kidney nerves to lower blood pressure. About 15 adults with high blood pressure who cannot take or tolerate standard medications will receive the procedure. The goal is to see if it is safe and can reduce blood pressure for up…

This study tests whether Songling Xuemaikang capsules can help control cerebral small vessel disease (CSVD), a condition where small blood vessels in the brain get damaged over time, often linked to high blood pressure. Researchers will enroll 90 adults aged 55-75 with hypertensi…

This study compares a newer blood pressure drug, sacubitril/allisartan, to the standard drug amlodipine in 104 overweight or obese adults with high blood pressure. Participants will take one of the two drugs for 8 weeks, with dose adjustments if needed. The main goal is to see wh…

This study tests whether tension and trauma releasing exercises (TRE) can improve quality of life and sleep in 40 adults aged 50-65 with stage 1 hypertension. Participants will do supervised TRE sessions for 8 weeks. Researchers will measure changes in sleep quality and well-bein…

This pilot study looks at how the diabetes and weight-loss drugs semaglutide and tirzepatide directly affect blood vessels and heart function, beyond their known effects on weight. Researchers will infuse the drugs into the arm or bloodstream of 112 volunteers with different body…

This early-stage study tests how two experimental drugs (BR1015-1 and BR1015-2) are processed by the body when taken together or as a combined tablet. It involves 48 healthy adults who will receive single doses under fed conditions. The goal is to measure drug levels and check fo…

This study looks at whether the natural drop in blood pressure during sleep (called 'dipping') is linked to changes in the heart's electrical activity in people with high blood pressure. Researchers will monitor 140 adults using a 24-hour blood pressure device and compare those w…