Hunt for childhood hypertension genes begins

NCT ID NCT06778239

Recruiting now Knowledge-focused Sponsor: National Human Genome Research Institute (NHGRI) Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This study aims to find genes that cause high blood pressure starting in childhood. Researchers will follow 2,300 people aged 2 and older, including those with childhood-onset hypertension and their healthy relatives, for up to 10 years. Participants provide blood, urine, and cheek swabs, and some children get extra tests like kidney ultrasounds. The goal is to understand genetic causes to develop better treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could identify genetic causes of childhood high blood pressure, pointing toward better treatments in the future.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear genetic links, and any benefits are years away.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

early onset hypertension essential hypertension hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESSENTIAL HYPERTENSION HYPERTENSION

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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