ESKETAMINE
Clinical trials for ESKETAMINE explained in plain language.
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Could a nasal spray after childbirth ward off postpartum depression?
Disease control Not yet recruitingThis study tests whether a nasal spray containing esketamine and dexmedetomidine, given twice after childbirth, can lower the chance of postpartum depression in women who already had mild depressive symptoms during pregnancy. Esketamine is a fast-acting antidepressant, and dexmed…
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New study aims to shield aging brains from Surgery's mental fog
Prevention Not yet recruitingThis long-term study follows older adults (65-90) who are having non-cardiac surgery to see if a combination of two drugs (dexmedetomidine and esketamine) plus a gentle brain stimulation technique (tDCS) can prevent memory and thinking problems that sometimes occur after surgery.…
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:32 UTC
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New study aims to stop Post-Surgery brain fog in seniors
Prevention Not yet recruitingThis study tests two approaches—a combination of medicines (dexmedetomidine and esketamine) and a gentle brain stimulation technique (tDCS)—to prevent confusion and memory problems after surgery in older adults. About 1,160 patients aged 65-90 with mild cognitive issues will be e…
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:31 UTC
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Could a nasal spray boost sleep and brain health in seniors?
Symptom relief Not yet recruitingThis study tests whether a nasal spray containing two medicines, dexmedetomidine and esketamine, can improve sleep quality and thinking abilities in older adults with mild-to-moderate Alzheimer's-related cognitive impairment and sleep problems. Sixty participants will receive eit…
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New drug cocktail aims to cut Post-Surgery pain in half
Symptom relief Not yet recruitingThis study tests whether giving a combination of two drugs, dexmedetomidine and esketamine, during and after spinal surgery can reduce moderate-to-severe pain in the first three days after the operation. About 274 adults aged 40 to 80 having spine surgery will be randomly assigne…
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Spine surgery pain breakthrough? drug cocktail aims to stop chronic ache
Symptom relief Not yet recruitingThis study tests whether giving a combination of two drugs (dexmedetomidine and esketamine) before and after spine surgery can lower the risk of long-term pain. About 274 adults aged 40-79 having spine surgery will take part. The goal is to see if this approach reduces pain that …
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Could a common anesthetic prevent post-surgery brain fog in seniors?
Symptom relief Not yet recruitingThis study tests whether a drug called esketamine can help prevent confusion and memory problems that sometimes happen after surgery in older adults. The trial will involve 120 people aged 65 to 90 who are having major non-cardiac surgery. Researchers will compare three different…
Matched conditions: ESKETAMINE
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC