New study aims to stop Post-Surgery brain fog in seniors

NCT ID NCT07576517

First seen May 12, 2026 · Last updated May 15, 2026 · Updated 1 time

Summary

This study tests whether giving older adults (65-90 years) a combination of two medicines (dexmedetomidine and esketamine) along with a gentle brain stimulation technique (tDCS) before and after surgery can prevent confusion and memory problems. About 1,160 participants will be followed to see if these treatments help protect their thinking skills. The goal is to find a safe way to reduce brain-related complications after non-cardiac surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affilited Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310006, China

    Contact Email: •••••@•••••

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian, 362011, China

    Contact Email: •••••@•••••

  • Peking University First Hospital

    Beijing, Beijing Municipality, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518036, China

    Contact Email: •••••@•••••

  • Second Affilited Hospital, School of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310009, China

    Contact Email: •••••@•••••

  • Xijing Hospital, Air Force Medical University

    Xi'an, Shaanxi, 710032, China

    Contact Email: •••••@•••••

Conditions

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