New study aims to stop Post-Surgery brain fog in seniors

NCT ID NCT07576517

Not yet recruiting Prevention Sponsor: Peking University First Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two approaches—a combination of medicines (dexmedetomidine and esketamine) and a gentle brain stimulation technique (tDCS)—to prevent confusion and memory problems after surgery in older adults. About 1,160 patients aged 65-90 with mild cognitive issues will be enrolled. The goal is to see if these methods can protect brain function during recovery.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEXMEDETOMIDINE ESKETAMINE OLDER PATIENTS PERIOPERATIVE NEUROCOGNITIVE DISORDERS SURGERY TRANSCRANIAL DIRECT CURRENT STIMULATION

Contacts and locations

Locations

First Affilited Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, 310006, China
Fujian Medical University Union Hospital

Fuzhou, Fujian, 362011, China
Peking University First Hospital

Beijing, Beijing Municipality, 100034, China
Peking University Shenzhen Hospital

Shenzhen, Guangdong, 518036, China
Second Affilited Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, 310009, China
Xijing Hospital, Air Force Medical University

Xi'an, Shaanxi, 710032, China

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