CROHN DISEASE

This study aimed to evaluate the long-term safety and effectiveness of the oral medication ozanimod for adults with moderate to severe Crohn's disease. It was an extension study for 854 participants who had already completed earlier phases of ozanimod research. The main goals wer…

This study tested whether following an anti-inflammatory whole-food diet for 8 weeks could help control Crohn's disease. It compared the diet to people's usual eating habits to see if it reduced symptoms and gut inflammation. The goal was to understand how diet affects the diseas…

This study tested whether treating a specific gut fungus with the antifungal drug posaconazole could reduce inflammation in people with active Crohn's disease who have a particular genetic risk (CARD9 S12N). It was a small, placebo-controlled trial that looked for improvements in…

This study tested whether a daily pill called ozanimod could help people with moderate to severe Crohn's disease stay in remission. It involved about 550 participants who had already responded to initial treatment. The main goal was to see if the pill could keep their symptoms lo…

This study tested whether a daily pill called ozanimod could help control symptoms and reduce gut inflammation in adults with moderate to severe Crohn's disease. It involved 625 participants whose current treatments weren't working well enough. The main goal was to see if the pil…

This study tested whether adding a new oral drug, BI 706321, to a standard Crohn's treatment (ustekinumab) could better control gut inflammation. About 50 adults with moderate to severe Crohn's disease were randomly assigned to take either the new drug or a placebo pill alongside…

This study tested whether the antibiotic rifaximin could reduce bloating symptoms in people with diabetic gastroparesis, a condition where the stomach empties too slowly. The small trial involved just 5 participants and was terminated early. Researchers measured symptom changes u…