COCAINE USE DISORDER
Clinical trials for COCAINE USE DISORDER explained in plain language.
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Can imagining your future curb cocaine cravings?
Disease control CompletedThis study tested whether a mental exercise called 'episodic future thinking' could help people with cocaine addiction. Participants practiced imagining positive future events in detail to see if it made them value long-term rewards more and reduced their desire for cocaine. Rese…
Matched conditions: COCAINE USE DISORDER
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Brain drug tested to curb cocaine cravings in opioid patients
Disease control CompletedThis small, early-stage study tested whether adding a low dose of the medication cariprazine to standard buprenorphine treatment could help people with both opioid and cocaine addiction use less cocaine. About 26 participants who were already stable on buprenorphine and not using…
Matched conditions: COCAINE USE DISORDER
Phase: PHASE2 • Sponsor: Kyle Kampman • Aim: Disease control
Last updated Mar 23, 2026 15:20 UTC
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Scientists test drug to block Cocaine's high
Disease control CompletedThis early-stage study tested whether a new oral medicine called STP7 (mavoglurant) changes how the body reacts to cocaine. Researchers gave 21 adults with cocaine use disorder either the medicine or a placebo, along with controlled doses of intravenous cocaine. The main goal was…
Matched conditions: COCAINE USE DISORDER
Phase: PHASE1 • Sponsor: Stalicla SA • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New shot at recovery: study tests monthly injections to curb cocaine cravings
Disease control CompletedThis study tested whether two long-acting, injectable medications—naltrexone and buprenorphine—could help people with cocaine use disorder reduce or stop their cocaine use. Over 400 adults participated in the 8-week trial, where half received the active medication injections and …
Matched conditions: COCAINE USE DISORDER
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Mar 09, 2026 14:22 UTC
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Can a pill erase painful memories? scientists test drug for trauma and addiction
Symptom relief CompletedThis study tested whether a drug called minocycline could help reduce the power of painful, intrusive memories in people with post-traumatic stress disorder (PTSD) or cocaine addiction. Researchers gave 138 participants either minocycline or a placebo pill before sessions where t…
Matched conditions: COCAINE USE DISORDER
Phase: NA • Sponsor: Psychiatric University Hospital, Zurich • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Brain scans could personalize addiction treatment for veterans
Knowledge-focused CompletedThis study aimed to understand how brain activity might predict which type of reward-based therapy works best for Veterans recovering from cocaine addiction. Researchers studied 63 Veterans to see if brain signals measured before treatment could indicate whether they would respon…
Matched conditions: COCAINE USE DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC