Can a supplement curb cocaine cravings during opioid withdrawal?
NCT ID NCT05610072
First seen Dec 18, 2025 · Last updated May 16, 2026 · Updated 21 times
Summary
This early-phase study looked at how brain glutamate levels change in people dependent on opioids who also use cocaine. Researchers tested whether the supplement N-acetylcysteine (NAC) could reduce cocaine and opioid demand during withdrawal. Twelve participants completed the study, which involved hypothetical drug purchasing tasks and brain scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Kentucky Department of Behavioral Science
Lexington, Kentucky, 40536-0086, United States
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University of Kentucky Laboratory of Human Behavioral Pharmacology
Lexington, Kentucky, 40507, United States
Conditions
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