Scientists hunt for addiction genes in 847 volunteers

NCT ID NCT01148381

Completed Knowledge-focused Sponsor: National Institute on Drug Abuse (NIDA) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 7 times

Summary

This completed study looked at how genes influence addiction and related behaviors. Researchers collected blood samples and had 847 adults (healthy volunteers, smokers, drug users, and people with psychiatric disorders) complete questionnaires and computer tasks. The goal was to link genetic information with brain imaging and behavioral data to better understand substance abuse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help identify genetic factors linked to addiction, potentially guiding future treatments or prevention strategies.
What could go wrong: This is an observational study, not a treatment trial. It does not test any intervention, so direct benefits are unlikely. Results may not lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence cocaine dependence nicotine dependence opiate dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY VOLUNTEERS SUBSTANCE USE DISORDERS

Contacts and locations

Locations

National Institute on Drug Abuse, Biomedical Research Center (BRC)

Baltimore, Maryland, 21224, United States

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