Brain scans may help tailor cocaine addiction treatment for veterans
NCT ID NCT03799341
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study looked at whether brain signals and thinking skills can predict how well Veterans with cocaine addiction respond to a behavioral therapy called contingency management. In this therapy, patients earn chances to win prizes for providing cocaine-free urine samples. The goal was to understand why some people benefit more than others and to help personalize treatment. The study involved 63 Veterans and measured brain activity before and during treatment.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Pittsburgh, Pennsylvania, 15240, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prize-Based Contingency Management (a behavioral therapy where patients earn chances to win prizes for cocaine-free urine tests)
What this could lead to
If successful, this could help doctors match Veterans with the most effective version of contingency management therapy for cocaine addiction, improving recovery rates.
What could go wrong
This is a small, early-stage study (63 participants) focused on measuring brain activity, not testing a new treatment. Results may not apply to all people with cocaine use disorder.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.