CHRONIC LYMPHOCYTIC LEUKEMIA
Clinical trials for CHRONIC LYMPHOCYTIC LEUKEMIA explained in plain language.
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New combo therapy aims to outsmart stubborn blood cancers
Disease control Not yet recruitingThis study tests a new drug, NX-5948, combined with other medicines for people with certain blood cancers (B-cell lymphoma, CLL, SLL) that have come back or not responded to prior treatment. About 150 adults will participate to see if the combination is safe and effective. The go…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 17, 2026 02:02 UTC
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New hope for hard-to-treat blood cancers: phase 3 trial compares two targeted drugs
Disease control Not yet recruitingThis study tests a new drug, NX-5948, against another drug, pirtobrutinib, in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose cancer has returned or stopped responding to a prior targeted therapy. About 620 adults will be randomly assigned…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE3 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New drug duo aims to wipe out hidden leukemia cells
Disease control Not yet recruitingThis study tests two oral drugs, nemtabrutinib and venetoclax, given together as the first treatment for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal is to see if the combination can clear even the tiniest traces of cancer from the …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Jennifer Woyach • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New combo therapy aims to improve outcomes for older CLL patients
Disease control Not yet recruitingThis study compares a fixed-duration combination of two drugs (zanubrutinib and sonrotoclax) against continuous zanubrutinib alone in older adults with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. The goal is to see if the combination improves how long pa…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New drug cocktail aims to deeply suppress blood cancer
Disease control Not yet recruitingThis study tests a combination of three drugs (acalabrutinib, venetoclax, and tafasitamab) in 35 adults with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. The goal is to see if the combo is safe and can achieve a complete response with undetecta…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Immune cell army targets Hard-to-Treat lymphoma
Disease control Not yet recruitingThis early-phase trial tests a new treatment for people with B-cell non-Hodgkin lymphoma that has not responded to at least two prior therapies. Participants receive donor immune cells (NK cells) along with two antibody drugs (rituximab and tafasitamab) to help the body fight the…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Paolo Caimi, MD • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Colombia launches first CAR-T trial for Hard-to-Treat blood cancers
Disease control Not yet recruitingThis study aims to bring CAR-T cell therapy to Colombia for people with certain blood cancers that have come back or not responded to treatment. It has two parts: first, setting up the necessary partnerships and facilities to produce the therapy locally, and second, a small trial…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: NA • Sponsor: GUSTAVO SALGUERO • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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CLL patients may pause cancer drugs without relapse
Disease control Not yet recruitingThis study looks at whether people with chronic lymphocytic leukemia (CLL) who have been in remission for at least two years can safely stop taking their BTK inhibitor medication. Researchers will track how long patients stay cancer-free without treatment, and whether stopping le…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 04, 2026 16:18 UTC
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New study aims to make allergy testing safer for cancer patients on biologics
Knowledge-focused Not yet recruitingThis study involves 70 patients with various cancers who are receiving biotherapy drugs. Researchers want to find the highest safe concentration of these drugs to use in skin allergy tests, so they can better diagnose allergic reactions. The goal is to create clear guidelines for…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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New study aims to fix unequal referrals for blood cancer patients
Knowledge-focused Not yet recruitingThis study surveys doctors and nurses to understand how they decide to refer patients with chronic lymphocytic leukemia (CLL) to specialists. Researchers will look for differences in referral patterns across the West Midlands region of the UK. The goal is to identify inequalities…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA
Sponsor: The Royal Wolverhampton Hospitals NHS Trust • Aim: Knowledge-focused
Last updated May 04, 2026 16:25 UTC