New hope for hard-to-treat blood cancers: phase 3 trial pits NX-5948 against standard therapy

NCT ID NCT07516093

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two drugs, NX-5948 and pirtobrutinib, in about 620 people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose cancer has returned or stopped responding after prior treatment with a BTK inhibitor. The main goal is to see which drug better delays disease progression or death. Participants will be randomly assigned to one of the two treatments.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••