BRADYCARDIA

This study tests a new setup method for a special pacemaker that delivers cardiac neuromodulation therapy to lower blood pressure. About 30 adults who already have or need a dual-chamber pacemaker and have high blood pressure will take part. The device's settings will be adjusted…

This study tests if a newer pacing method (physiological pacing) is better than the standard method for people with a slow heart rate. About 2,600 adults who need a pacemaker will be randomly assigned to one of the two methods. The goal is to see which approach reduces the risk o…

This study follows 1,805 people who already have an Aveir DR leadless pacemaker to see how safe it is over 5 years. The pacemaker helps control slow heart rhythms without wires. Researchers will track complications shortly after implant and for years afterward using real-world da…

This study compares a new pacing method (conduction system pacing) to standard care in 120 adults with bradycardia (slow heart rate) and wide QRS (a sign of electrical delay in the heart). The goal is to see if the new method better prevents a drop in the heart's pumping ability …

This study is testing a new, wire-free pacemaker called LivIQ in 325 people who need a pacemaker for a slow heartbeat. The goal is to see if it is safe and works well to keep the heart beating at the right pace. Participants will be followed for several months to check the device…

This study looks at how safe and effective a new pacemaker lead is for people with bradycardia (slow heart rate). About 140 adults who need a pacemaker will get the lead and be followed over time. The goal is to see if it helps the heart beat in a more natural way.

This study is testing a new way to pace the heart called left bundle branch area pacing (LBBAP) in 200 people who need a pacemaker for conditions like slow heartbeat or heart failure. The goal is to see if this method is safe and works better than standard pacing over 6 months. R…

This study tests a new device called UHF-ECG that uses ultra-high frequency signals to check if the heart's lower chambers are beating in sync. It involves 360 adults with slow heartbeats or heart failure who are scheduled to get a pacemaker. The goal is to see if this new method…

This study compares three sedation protocols (dexmedetomidine, propofol, or both) in 1,000 adults having cataract surgery. The goal is to see which approach provides the best sedation with the fewest side effects like low blood pressure or nausea. Participants will be monitored d…

This study compares two ultrasound-guided nerve blocks to see which one makes it easier for patients to get into position for spinal anesthesia and provides longer pain relief after thigh or knee surgery. Sixty adults aged 30 to 60 will be randomly assigned to receive one of the …

This study tests whether adjusting a pacemaker to each patient's ideal heart rate can reduce heart failure symptoms. About 106 adults with heart failure and slow heart rates will receive either standard or personalized pacemaker settings. The goal is to see if the tailored approa…

This study compares two types of ultrasound-guided nerve blocks (S-FICB and PENG) to see which one better reduces pain when positioning patients for spinal anesthesia during femur fracture surgery. About 70 adults aged 20-70 with a broken femur will be enrolled. The goal is to ma…

This study tests whether adding dexmedetomidine or dexamethasone to a standard numbing medicine (ropivacaine) helps pain relief start faster during arm surgery. About 66 adults having upper limb surgery will receive one of the two combinations. The goal is to see which approach p…

This study will follow 1000 people with a slow heartbeat (bradycardia) who already have a specific type of pacemaker. The pacemaker will track sleep-related breathing problems and daily activity over time. Researchers want to see if this information can predict serious heart even…

This study monitors how long Medtronic heart devices (like pacemakers) last and how often they have problems. It includes up to 20,000 people who have or will get one of these devices. The goal is to collect real-world data to improve future device safety and performance.

This study is for people with heart failure or a slow heartbeat who are already scheduled to get a pacemaker. Researchers will take extra measurements during the procedure to see if pacing a specific part of the heart (the His bundle) can improve electrical conduction. The goal i…

This study watches how well a small heart monitor (BIOMONITOR III) works in routine medical care for 1400 people. It tracks how quickly the device finds hidden heart rhythm problems like atrial fibrillation or fainting spells. The goal is to learn about the device's real-life per…

This study looks at whether playing sounds similar to what babies hear in the womb can help preterm infants develop better control over their breathing. Researchers will monitor 34 preterm babies born at 29-33 weeks to see how sound exposure affects breathing pauses, low oxygen l…

This study tests a portable ECG system that helps doctors monitor the placement of a pacing lead in the heart during a pacemaker or similar device implantation. About 55 adults who need this procedure will take part. The goal is to see if the portable system works as well as stan…

This study looks at the electrical signals in the heart during a specific pacing method called left bundle branch area pacing (LBBAP). The goal is to learn how these signals change with different pacing strengths and body positions. This information could help create a smarter pa…