BIPOLAR DEPRESSION
Clinical trials for BIPOLAR DEPRESSION explained in plain language.
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New hope for Long-Term bipolar depression treatment
Disease control ENROLLING_BY_INVITATIONThis study aims to understand the long-term safety and effectiveness of the drug azetukalner for adults with bipolar depression. It is open to 400 participants who successfully completed a previous Phase 3 trial of the same drug. The main goal is to monitor side effects and see i…
Matched conditions: BIPOLAR DEPRESSION
Phase: PHASE3 • Sponsor: Xenon Pharmaceuticals Inc. • Aim: Disease control
Last updated Apr 02, 2026 03:41 UTC
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Can a daily dose of bright light lift the fog of bipolar depression?
Symptom relief OngoingThis study is testing whether adding daily bright light therapy to standard medication helps people with bipolar depression who naturally prefer evenings ('night owls'). Over six weeks, 70 participants will use either a real bright light device or a placebo device for 30 minutes …
Matched conditions: BIPOLAR DEPRESSION
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Can exercise speed recovery from bipolar depression?
Symptom relief TerminatedThis study is testing if adding supervised aerobic exercise to standard medication helps people with bipolar depression recover faster and prevents future episodes. It will involve 54 participants who are randomly assigned to either an exercise group, a relaxation group, or an in…
Matched conditions: BIPOLAR DEPRESSION
Phase: NA • Sponsor: Region Stockholm • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Scientists scan brains to unlock clues for treating bipolar depression
Knowledge-focused OngoingThis study aims to understand how a magnetic stimulation treatment affects the brain in older adults with bipolar depression. Researchers will use brain scans before and after treatment to measure changes in brain activity. The goal is to gather information that could help guide …
Matched conditions: BIPOLAR DEPRESSION
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Scientists map Lithium's effects on the bipolar brain
Knowledge-focused OngoingThis study aims to understand how lithium, a common treatment for bipolar disorder, changes the brain's wiring and activity. Researchers will use MRI brain scans on about 120 people with bipolar depression and healthy volunteers over 26 weeks to see how brain connections shift wi…
Matched conditions: BIPOLAR DEPRESSION
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC