Brain wave clues may unlock ECT success in tough depression cases
NCT ID NCT04451135
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether brain wave patterns recorded during and after electroconvulsive therapy (ECT) can predict how much depression symptoms improve. About 31 adults with treatment-resistant depression will have their brain activity measured with a wearable EEG device. The goal is to find markers that could help personalize ECT treatment in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better predict who will respond to ECT and improve treatment planning for severe depression.
- What could go wrong
- This is a small, early-stage observational study (31 participants) that only looks for patterns, not a new treatment. Results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Washington University School of Medicine/Barnes-Jewish Hospital
St Louis, Missouri, 63110, United States
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