Brain wave clues may unlock ECT success in tough depression cases
NCT ID NCT04451135
First seen Jan 04, 2026 · Last updated Jun 23, 2026 · Updated 30 times
Summary
This study looks at whether brain wave patterns recorded during and after electroconvulsive therapy (ECT) can predict how much depression symptoms improve. About 31 adults with treatment-resistant depression will have their brain activity measured with a wearable EEG device. The goal is to find markers that could help personalize ECT treatment in the future.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Washington University School of Medicine/Barnes-Jewish Hospital
St Louis, Missouri, 63110, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors better predict who will respond to ECT and improve treatment planning for severe depression.
What could go wrong
This is a small, early-stage observational study (31 participants) that only looks for patterns, not a new treatment. Results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.