BIPOLAR DEPRESSION
Clinical trials for BIPOLAR DEPRESSION explained in plain language.
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New hope for bipolar depression? pramipexole trial targets anhedonia
Symptom relief Not yet recruitingThis Phase 3 trial tests whether pramipexole, a dopamine-boosting drug, can ease anhedonia (loss of pleasure) in people with bipolar depression. 126 participants will receive either pramipexole or a placebo alongside their usual mood stabilizer for 6 weeks. The study aims to impr…
Matched conditions: BIPOLAR DEPRESSION
Phase: PHASE3 • Sponsor: Daniel Lindqvist • Aim: Symptom relief
Last updated Jul 02, 2026 02:00 UTC
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Could Anti-Inflammatory drugs lift depression?
Symptom relief Not yet recruitingThis study tests whether two anti-inflammatory medications, celecoxib or minocycline, can reduce depression symptoms in adults with major depressive disorder or bipolar depression. About 42 participants will take one of the drugs for 8 weeks and have their depression levels measu…
Matched conditions: BIPOLAR DEPRESSION
Phase: PHASE4 • Sponsor: Stony Brook University • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a diabetes pill lift bipolar depression? small study aims to find out
Symptom relief Not yet recruitingThis study tests whether empagliflozin, a drug used for diabetes, can help reduce depression in people with bipolar disorder who also have insulin resistance. Twenty adults with bipolar depression will take the drug for 12 weeks alongside their usual treatment. The goal is to see…
Matched conditions: BIPOLAR DEPRESSION
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC