Shock vs magnet: which therapy is safer for depression?

NCT ID NCT05054699

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two brain stimulation treatments—electroconvulsive therapy (ECT) and magnetic seizure therapy (MST)—for people with severe depression that hasn't improved with standard medications. About 100 adults with major depression or bipolar depression will receive one of the two treatments. The goal is to see which works better for mood and causes fewer memory problems.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute of Psychiatry, HC-FMUSP

    São Paulo, São Paulo, Brazil

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