BARRETT ESOPHAGUS

This study is testing a device that freezes and destroys abnormal cells in the esophagus (a condition called Barrett's esophagus) in patients where standard heat-based treatments have not worked well. About 70 participants will have the freezing treatment every few months for up …

This study is testing whether a small, swallowable capsule attached to a thin string can effectively screen for Barrett's esophagus in primary care clinics. The capsule takes microscopic pictures of the esophagus during a 10-minute procedure without sedation. Researchers want to …

This study is testing a new, simpler device called Endosign to see if it can be used instead of regular endoscopies to monitor people with Barrett's esophagus, a condition that can lead to esophageal cancer. The device is swallowed like a capsule to collect a small tissue sample,…

This study is testing a new, simpler way to screen for Barrett's esophagus and esophageal cancer. Researchers are using a small sponge on a string that patients swallow, which collects cells from the esophagus. They are checking if lab tests on these cells can accurately spot dan…

This study aimed to test a new, swallowable camera capsule to diagnose conditions like eosinophilic esophagitis (EoE). The goal was to see if images from the capsule were as good as those from standard, invasive biopsy procedures that require sedation. The trial was withdrawn bef…

This study is testing whether a daily aspirin pill can help prevent Barrett's esophagus from returning after it has been successfully treated with a procedure called radiofrequency ablation. It involves 21 people who have had their Barrett's esophagus cleared. Participants are ra…

This early study aims to understand how two existing constipation medications affect a specific chemical signal in the small intestine. Researchers will compare tissue samples from volunteers who take a single dose of either drug or no drug before a scheduled medical procedure. T…

This study aims to better understand how Barrett's Esophagus changes over a 3-year period. Researchers will follow 500 participants at five US medical centers using a special swallowable capsule with a tiny camera to take images of the esophagus. The goal is to track the size and…

This study is creating a registry to collect information from 2,000 people with chronic heartburn (GERD) and related conditions. Participants will be followed for 5 years to gather data on their symptoms, treatments, and long-term health. The goal is to better understand how thes…

This study aims to find early DNA changes in blood and tissue that might warn when Barrett's esophagus is turning into cancer. Researchers are analyzing samples from 600 people with acid reflux, Barrett's esophagus, or esophageal cancer to identify these warning signs. The goal i…

This study aims to better understand how Barrett's esophagus changes over time. Researchers will follow 100 participants for three years using a special swallowable camera that takes images of the esophagus. The goal is to gather detailed information about the natural progression…