BARRETT ESOPHAGUS

This study tests a freezing device (CryoBalloon) to treat Barrett's esophagus in people who still have abnormal cells after several standard heat treatments. About 70 adults with precancerous changes in the esophagus will receive the freezing treatment. The goal is to see if it c…

This study tests a simple, less invasive screening tool—a sponge on a string—to detect Barrett's esophagus and esophageal cancer. Researchers aim to see if DNA markers from the sponge sample can accurately identify high-grade dysplasia and cancer. About 450 adults with Barrett's …

This study explores whether a device called Endosign, which collects tissue samples from the mouth, can reliably monitor Barrett's esophagus—a condition that can lead to esophageal cancer. Current monitoring requires regular endoscopies, which are uncomfortable and costly. The st…

This study is testing a new, less invasive way to screen for Barrett's esophagus, a condition that can lead to esophageal cancer. Participants will swallow a small capsule with a camera that takes pictures of the esophagus. The goal is to see if this method is comfortable and wor…

This phase 2 trial tests whether taking aspirin can prevent Barrett's esophagus from returning after it has been successfully removed with radiofrequency ablation. About 21 participants will take either aspirin or a placebo for 12 months. Researchers will measure specific protein…

This study is creating a long-term registry of 2,000 people with gastroesophageal reflux disease (GERD) and related conditions like Barrett's esophagus. Researchers will collect information from medical records and questionnaires over 5 years to better understand how GERD is diag…

This study aimed to see if a special camera inside a pill-sized capsule could diagnose eosinophilic esophagitis and Barrett esophagus as well as standard biopsy. It planned to include healthy adults and teens being checked for these conditions. However, the study was withdrawn be…

This study follows 500 adults with Barrett's esophagus, a condition that can lead to esophageal cancer, for 3 years. Researchers use a tethered capsule endomicroscopy device, a pill-sized camera that takes detailed images of the esophagus, to measure changes in the affected area.…

This study looks for early DNA changes in blood and tissue that might warn of esophageal cancer in people with Barrett's esophagus or chronic reflux. Researchers will follow 600 participants over time to see if these markers can predict cancer progression. The goal is to improve …

This study looks at 200 FDNY rescue workers who were exposed to dust and toxins at the World Trade Center site. Many developed heartburn, breathing issues, and a condition called Barrett's esophagus that can raise cancer risk. Researchers will use simple tests like saliva samples…

This study follows 100 adults with Barrett's esophagus, a condition where the lining of the food pipe changes, to see how it naturally progresses. Participants swallow a small camera in a capsule that takes pictures of the esophagus during routine check-ups. The goal is to learn …