BARRETT ESOPHAGUS
Clinical trials for BARRETT ESOPHAGUS explained in plain language.
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Sponge on a string and AI could revolutionize esophageal cancer screening
Diagnosis Not yet recruitingThis study will test whether a combination of an AI-powered risk tool, a simple 'sponge on a string' test, and nurse navigation can improve screening for Barrett's esophagus and esophageal cancer. Over 1,000 adults at higher risk will be enrolled. The goal is to see if these less…
Matched conditions: BARRETT ESOPHAGUS
Phase: NA • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Could a fungal drug stop esophageal cancer before it starts?
Prevention Not yet recruitingThis study tests whether adding the antifungal drug itraconazole to standard ablation therapy can prevent esophageal cancer in people with high-risk Barrett's esophagus. About 64 participants will receive either itraconazole or a placebo alongside their usual endoscopic ablation.…
Matched conditions: BARRETT ESOPHAGUS
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Jun 27, 2026 12:32 UTC
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Spit test may spot reflux risk after gastric sleeve surgery
Knowledge-focused Not yet recruitingThis study looks at whether measuring bile acids and pepsin in saliva can help identify people who develop acid reflux or esophageal damage after sleeve gastrectomy (a type of weight-loss surgery). About 60 adults will give saliva samples before surgery and again 1 and 3 years af…
Matched conditions: BARRETT ESOPHAGUS
Sponsor: Hospital de Mataró • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Genetic risk profiles could change how we monitor Barrett's esophagus
Knowledge-focused Not yet recruitingThis study looks at whether sharing genetic risk information with Barrett's esophagus patients can improve their quality of life and reduce cancer worry. Researchers will collect tissue samples and use genetic analysis to create risk profiles. Half of the 266 participants will le…
Matched conditions: BARRETT ESOPHAGUS
Phase: NA • Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC