ALS (AMYOTROPHIC LATERAL SCLEROSIS)

This early-stage study is testing the safety of a new gene therapy called CTx1000 in people with ALS. The therapy aims to target a protein called TDP-43 that builds up in ALS. Researchers will give a single dose to 15 participants and closely monitor for side effects while also c…

This program provides the experimental drug SPG302 to adults with ALS who cannot join other clinical trials. It aims to assess the drug's safety and whether it helps slow the disease. Participants must have some remaining lung function and be on stable ALS medications if currentl…

This study is testing a new combination treatment for people with ALS (amyotrophic lateral sclerosis). It aims to see if using a non-invasive brain stimulation technique along with personalized mixed reality exercise games can help slow down the disease and improve daily life. Th…

This is an early safety study to test a new drug called LY4256984 for people with sporadic ALS. The drug is injected into the spine. Researchers will check for side effects and measure how much of the drug gets into the blood and spinal fluid.

This study is testing whether tofersen, a drug already approved for a specific genetic form of ALS, is safe and can lower a key disease marker in people with ALS who do not have that specific gene mutation. About 30 adults with early-stage ALS will receive the drug via spinal inj…

This study is testing a non-invasive device called the MyoRegulator to see if it is safe and feasible for people with ALS (Lou Gehrig's disease). The device uses gentle electrical stimulation to try to calm overactive motor nerve cells, which is a key problem in ALS. Researchers …

This study is testing a special fabric shoulder brace designed to mimic muscle support. It aims to see if wearing this device helps people with conditions like muscular dystrophy or ALS perform arm movements needed for daily tasks, such as reaching or brushing hair. Researchers w…

This study is creating a national registry to collect detailed information from 100 ALS patients across Thailand. Researchers will track how the disease progresses, what treatments patients receive, and how genetics might affect outcomes. No experimental treatments are being test…

This study aims to better understand diseases like Alzheimer's and Parkinson's by analyzing the genes, proteins, and other molecules in people who have them. Researchers will collect blood and other samples from 1200 participants to look for patterns that could lead to new ways t…

This study aims to create a standard test to measure how well different assistive technologies and brain-computer interfaces help people with severe motor impairments from spinal cord injury or ALS use computers and phones. Researchers will have 60 participants, including people …