ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Clinical trials for ALS (AMYOTROPHIC LATERAL SCLEROSIS) explained in plain language.
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New ALS drug trial aims to tame inflammation
Disease control Not yet recruitingThis early-phase trial tests an oral drug, Kamlanoflast, in 40 people with ALS. Over 24 weeks, researchers will check safety, tolerability, and whether the drug reduces inflammation and slows decline in function. It is not yet recruiting.
Matched conditions: ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Phase: PHASE1, PHASE2 • Sponsor: Inflammasome Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New drug combo targets ALS inflammation in genetically selected patients
Disease control Not yet recruitingThis study tests whether combining two drugs (galunisertib and nerandomilast) can slow the progression of ALS in 60 people who have high levels of a protein called GREM2. The drugs aim to reduce brain inflammation and nerve cell damage. Participants will receive either the drug c…
Matched conditions: ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Phase: PHASE2, PHASE3 • Sponsor: Gipfel Life Sciences GmbH • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Blood platelets may hold key to faster ALS diagnosis
Diagnosis Not yet recruitingThis study aims to find specific markers in blood platelets that can help doctors diagnose ALS (Lou Gehrig's disease) more accurately and earlier. Researchers will compare 60 participants—30 with newly diagnosed ALS and 30 with other motor neuron diseases—to see if platelet tests…
Matched conditions: ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Sponsor: University Hospital, Tours • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Can VR breathing calm anxiety in ALS? new study aims to find out
Symptom relief Not yet recruitingThis study tests whether a home-based virtual reality guided breathing program can reduce anxiety and improve quality of life in people with ALS. Sixty participants will use a VR headset to follow breathing exercises. The goal is to see if this simple, immersive tool can help man…
Matched conditions: ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Phase: NA • Sponsor: Horizon Health Network • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Mind-Controlled apple vision pro could help paralyzed people speak
Symptom relief Not yet recruitingThis study will test a new device that combines a brain-sensing headband with Apple's Vision Pro goggles to help people with ALS, brain injury, or spinal cord injury communicate. Up to 10 participants will use the system for 3-4 months to see how well they can type and control a …
Matched conditions: ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Phase: NA • Sponsor: Cognixion • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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New ALS screening study aims to Fast-Track patients to trials
Knowledge-focused Not yet recruitingThis observational study screens 500 people with early-stage ALS to see if they qualify for specific early-phase clinical trials. Participants undergo tests, genetic analysis, and biomarker checks to match them with the right trial. The study also builds a research database for f…
Matched conditions: ALS (AMYOTROPHIC LATERAL SCLEROSIS)
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC