Vitamin deficiency disorder

This study looks at whether giving a higher dose of vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) can improve their health. Researchers will check vitamin D levels and measure effects on the lungs, bones, immune system…

This study looks at whether giving extra vitamin D (800 IU daily) to extremely premature infants (born before 28 weeks or weighing under 1000 grams) improves their lung, bone, immune, and brain health. About 180 babies will receive either the extra vitamin D or usual care for the…

This study tests whether giving pregnant women a daily vitamin B12 supplement (50 micrograms) from early pregnancy until six months after birth helps their children grow and think better. Researchers are enrolling 800 pregnant women in Nepal who are at risk of low B12 levels. The…

This study tests whether adding high-dose vitamin D3 to standard anti-TNF therapy can improve symptoms and reduce inflammation in people with active Crohn's disease or ulcerative colitis. About 100 adults starting anti-TNF treatment will receive either vitamin D3 or a placebo for…

This study tests whether a pharmacist-led education program can help women with hypothyroidism and low vitamin D levels improve their vitamin D levels and medication habits. Sixty women will be split into two groups: one receives standard care, the other gets counseling, brochure…

This Phase II trial tests whether high-dose vitamin D (4,000 IU daily) can correct deficiency and slow cognitive decline better than standard doses in 180 older adults aged 65-90. Participants include those with normal thinking, mild impairment, or early Alzheimer's. The study la…

This study compares two different doses of vitamin D supplements in 108 adults with type 2 diabetes who also have low vitamin D levels. Researchers will measure changes in blood sugar and HbA1c over time to see if higher doses improve diabetes control. Participants must be aged 4…

This study tests whether giving a single high-dose vitamin D pill to patients with low vitamin D levels before hip or knee replacement surgery can reduce complications like infection. About 200 adults with osteoarthritis and vitamin D deficiency will receive 300,000 IU of vitamin…

This study tests whether vitamin D3 supplements can improve asthma control in adolescents aged 12-17 who have obesity, non-allergic asthma, and vitamin D deficiency. Participants receive either a high or standard daily dose of vitamin D3 for three months. Researchers will measure…

This study offers voluntary screening for newborns in North Carolina to detect a wide range of rare health conditions early. Using a small blood sample already collected at birth, the program tests for dozens of disorders, including spinal muscular atrophy, cystic fibrosis, and m…

This study tests whether phentolamine eye drops can improve vision in low light for people who had laser eye surgery and now see glare, halos, or starbursts at night. About 200 adults will use the drops or a placebo every evening for two weeks. The main goal is to see if more peo…

This study looks at whether taking vitamin D can reduce nerve pain caused by chemotherapy in people with low vitamin D levels. About 120 cancer patients will be split into two groups: one gets vitamin D supplements, the other gets standard care. The goal is to see if vitamin D he…

This study tests whether taking vitamin D3 before a root canal can reduce pain afterward. Fifty-four adults with low vitamin D and painful tooth inflammation will receive either a single high dose, a three-day course, or a placebo. Pain levels and painkiller use will be tracked f…

This study looks at whether giving vitamin D supplements to women with depression and low vitamin D levels can change their brain waves. Researchers will measure brain activity using a non-invasive EEG scan before and after supplementation. The trial includes 34 women aged 20-40 …

This study looks at how well children aged 1 to 16 tolerate and accept new nutritional feeds made from real food ingredients. The feeds are given through a tube or as a drink. Researchers will track stomach issues like pain, bloating, and nausea over 28 days. The goal is to see i…

This study looks at whether vitamin C can increase body heat produced by the nervous system and boost vitamin D levels in the blood. Researchers will measure temperature and blood samples in 20 overweight adults aged 18-40 during a stimulation test. The goal is to understand how …

This study looks at whether storing blood samples (frozen or at different temperatures) changes the accuracy of a vitamin D test called the ALPCO 25(OH) Vitamin D CLIA Kit. Researchers will compare results from fresh blood with those from stored samples in 80 healthy adults. The …

This study aimed to find the right daily dose of vitamin C for older people living in care homes, who often have low levels of this immune-supporting nutrient. The goal was to gather data for a future trial on whether vitamin C could help reduce the risk and severity of respirato…

This study tests three different daily doses of vitamin B12 (2.6, 10, and 50 micrograms) in 40 pregnant women and 10 non-pregnant women in Tanzania. The goal is to see how the body processes B12 during pregnancy and find the optimal dose for future larger trials. Participants tak…

This study looks at whether a new vitamin B12 supplement, natural orange extract, or a mix of both can boost physical and mental performance. It involves 20 healthy, well-trained men aged 18-45 who regularly eat citrus fruits. Participants will do intense bike tests and reaction-…

This study looks at how vitamin D levels might influence high blood pressure in people with type 2 diabetes. Researchers will collect blood samples from 40 participants to study immune cells called monocytes and see if they trigger a hormone that raises blood pressure. The goal i…

This study looks at vitamin A levels in 90 adults with vocal fold leukoplakia, a condition that causes white patches on the vocal cords. Researchers want to see if vitamin A status differs between people with and without precancerous changes. Participants provide blood and tissue…

This study looks at whether low vitamin D in pregnant women affects the baby's brain development. Researchers will use ultrasound to compare brain images of 100 women with and without vitamin D deficiency. The goal is to understand possible effects during the second and third tri…

This study looks at whether vitamin D levels in the blood affect bone loss around dental implants that support lower dentures. Researchers will measure bone changes and gum health in 40 adults aged 40-60 who already have these implants. The goal is to understand if vitamin D help…