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What's the best vitamin B12 dose for pregnancy? new study aims to find out

NCT ID NCT05426395

Ongoing Knowledge-focused Sponsor: George Washington University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests three different daily doses of vitamin B12 (2.6, 10, and 50 micrograms) in 40 pregnant women and 10 non-pregnant women in Tanzania. The goal is to see how the body processes B12 during pregnancy and find the optimal dose for future larger trials. Participants take the supplement for four weeks, and researchers measure B12 levels in the blood to determine the best dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Vitamin B12
What this could lead to
If successful, this study could identify the best vitamin B12 dose for pregnant women, improving maternal and fetal health in areas where deficiency is common.
What could go wrong
This is a small, early-phase trial (50 participants) focused on dosing and biomarkers, not on health outcomes. The results may not apply to other populations or lead to immediate treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

vitamin B12 deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VITAMIN B 12 DEFICIENCY

Contacts and locations

Locations

  • Ifakara Health Institute Bagamoyo Clinical Trial Unit (BCTU)

    Bagamoyo, Tanzania

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Other studies related to the condition(s) this trial covers.