Could a daily vitamin fix B12 deficiency in diabetes patients?

NCT ID NCT06983223

Completed Disease control Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special oral vitamin B12 supplement (Sucrosomial® B12) can raise B12 levels in people with type 2 diabetes who have low B12 due to taking metformin. Fifty adults took either the supplement or a placebo daily for 3 weeks. The goal was to see if the supplement could correct the deficiency and improve related blood markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sucrosomial® Vitamin B12 (an oral vitamin B12 supplement)
What this could lead to: If it works, this could offer a simple, daily supplement to manage B12 deficiency in people with type 2 diabetes who take metformin.
What could go wrong: This is a small, short-term study (50 people, 4 weeks). Results may not apply to everyone, and the supplement may not work better than placebo.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus vitamin B12 deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS (T2DM) VITAMIN B 12 DEFICIENCY

Contacts and locations

Locations

Liaquat University of Medical & Health Sciences (LUMHS)

Jāmshoro, Sindh, 76090, Pakistan

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