Varicose disease

This phase 3 trial compares two laser wavelengths (1940 nm vs 1470 nm) for closing off faulty veins in people with symptomatic varicose veins. 220 adults will be randomly assigned to one laser or the other. The main goal is to see which laser achieves complete vein closure at 6 m…

This study tests whether beta-blockers, a type of blood pressure medicine, can reduce the risk of bleeding from small varices in people with cirrhosis and portal hypertension. About 763 adults with small varices will receive either beta-blockers or a placebo for up to 3 years. Th…

This study looks at whether giving pantoprazole (a stomach acid reducer) after endoscopic treatment for enlarged veins in the esophagus or stomach can lower the chance of bleeding in people with liver cirrhosis. About 208 adults will take part. The goal is to see if short-term us…

This study looks at 70 people with liver cancer who had bleeding from enlarged veins in the esophagus. It compares two procedures—an ultrasound-guided injection of a glue-like substance versus a banding technique—to see which better prevents future bleeding. The goal is to find t…

This study tests whether carvedilol, a newer blood pressure drug, works better than the standard drug propranolol for preventing another bleeding episode in people with liver cirrhosis who have already had variceal bleeding. Both drugs are given alongside a procedure to tie off s…

This study is testing a new, less invasive way to perform surgery for grade III hemorrhoids. The goal is to see if using special tools to see and work better inside the body can reduce pain and help people recover faster after surgery. Twenty adults with advanced hemorrhoids will…

This trial tests whether wearing compression stockings with a higher (32 mmHg) or lower (21 mmHg) pressure after radiofrequency ablation for varicose veins leads to less pain and swelling. About 64 adults with varicose veins and leg swelling will wear one of the two stocking type…

This study tests whether using argon plasma coagulation during hemorrhoid surgery can reduce pain and complications compared to standard methods. About 100 adults with severe hemorrhoids will be randomly assigned to one of two surgical techniques. Pain levels and recovery will be…

This study looks at whether wearing compression stockings for a longer time after foam sclerotherapy (a treatment for varicose veins) can reduce skin darkening (hyperpigmentation) above the treated veins. About 140 adults with varicose veins will be followed for 28 days after the…

This study planned to compare a minimally invasive version of open hemorrhoidectomy to the standard technique in adults with grade III hemorrhoids. The goal was to see if the newer approach causes less pain after surgery. However, the trial was withdrawn before any participants w…

This study surveys doctors who use Concerto Versa detachable coils to treat various blood vessel conditions like aneurysms and varicose veins. About 30 patients will be included, and doctors report how well the coils work and any problems within 72 hours. The goal is to collect e…

This study aims to create and test a new scoring system called HeQAS that uses a microscope to evaluate the technical quality of hemorrhoid removal surgery. Researchers will check if the score is reliable and whether a newer, less invasive surgical method causes less tissue damag…

This trial is testing a medical device that has not been approved or cleared by the U.S. FDA. The study is small and early-stage, focused on understanding how the device works and whether it is safe. No results are available yet, and the device is not ready for widespread use.

This study looks at how often pelvic congestion syndrome (a condition where veins in the pelvis become enlarged and painful) occurs in women who are about to have a standard procedure for leg varicose veins. Researchers want to know if having this pelvic condition affects how muc…

This study follows 100 people with and without varicose veins to see how often the condition appears and how it changes over time. Participants get yearly checkups including ultrasound exams. The goal is to learn what factors make vein disease worse and how it naturally progresse…

This study looks at how straining affects people with bleeding hemorrhoids. Researchers will use surveys and a standard test called anorectal manometry to understand the link between pelvic floor problems and hemorrhoid symptoms. The goal is to help doctors give better treatment …

This study looks at data from 100 adults who had hemorrhoid surgery. Researchers will use machine learning to find patterns and group patients by shared traits like age, symptoms, and surgery type. The goal is to see if these groups have different surgical experiences, which coul…

This study was designed to test a holistic education program for stress management in people from colonized English-speaking countries. It aimed to help with conditions like stress, PTSD, anxiety, and fatigue using pastoral counseling and self-care activities. However, the study …