Varicose disease
MONDO:0008638A vascular disease characterized by the presence of enlarged and tortuous veins.
Also known as: varix, varices, varicose veins
295 clinical trials for this condition and its sub-types.
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Broader categories
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Glue vs. heat vs. knife: which vein fix wins?
Disease control TerminatedThis study tested a medical glue called VenaSeal against heat therapy or surgery for treating venous reflux, a condition where leg veins don't pump blood properly. About 500 adults with early to advanced vein disease took part. The goal was to see which method patients liked more…
Phase: NA • Sponsor: Medtronic Endovascular • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Shorter infusion may be just as good for preventing repeat variceal bleeding
Disease control TerminatedThis study looked at whether giving the drug octreotide for 24 hours instead of the usual 72 hours could prevent early rebleeding from esophageal varices in people with cirrhosis. The trial included 34 adults with active bleeding from varices who underwent endoscopic banding. The…
Phase: PHASE4 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Experimental drug aims to prevent bleeding veins in fatty liver disease
Prevention TerminatedThis study tested a drug called belapectin to see if it could prevent the formation of esophageal varices (enlarged veins in the esophagus) in people with NASH cirrhosis and signs of high blood pressure in the liver. The trial enrolled 357 adults and compared belapectin to a plac…
Phase: PHASE2, PHASE3 • Sponsor: Galectin Therapeutics Inc. • Aim: Prevention
Last updated Jul 02, 2026 00:00 UTC
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Varicose vein treatment showdown: foam vs. heat
Symptom relief TerminatedThis study compared two treatments for varicose veins: Varithena (a foam) and Endothermal Ablation (using heat). It included 43 adults with a faulty great saphenous vein. The goal was to see which treatment better reduced symptoms like heaviness and pain over 3 months.
Phase: PHASE4 • Sponsor: Boston Scientific Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC