Varicose disease
MONDO:0008638A vascular disease characterized by the presence of enlarged and tortuous veins.
Also known as: varix, varices, varicose veins
172 clinical trials for this condition and its sub-types.
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Broader categories
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Glue vs. heat vs. knife: which vein fix wins?
Disease control TerminatedThis study tested a medical glue called VenaSeal against heat therapy or surgery for treating venous reflux, a condition where leg veins don't pump blood properly. About 500 adults with early to advanced vein disease took part. The goal was to see which method patients liked more…
Phase: NA • Sponsor: Medtronic Endovascular • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Shorter infusion may be just as good for preventing repeat variceal bleeding
Disease control TerminatedThis study looked at whether giving the drug octreotide for 24 hours instead of the usual 72 hours could prevent early rebleeding from esophageal varices in people with cirrhosis. The trial included 34 adults with active bleeding from varices who underwent endoscopic banding. The…
Phase: PHASE4 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Experimental drug aims to prevent bleeding veins in fatty liver disease
Prevention TerminatedThis study tested a drug called belapectin to see if it could prevent the formation of esophageal varices (enlarged veins in the esophagus) in people with NASH cirrhosis and signs of high blood pressure in the liver. The trial enrolled 357 adults and compared belapectin to a plac…
Phase: PHASE2, PHASE3 • Sponsor: Galectin Therapeutics Inc. • Aim: Prevention
Last updated Jul 02, 2026 00:00 UTC
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Varicose vein treatment showdown: foam vs. heat
Symptom relief TerminatedThis study compared two treatments for varicose veins: Varithena (a foam) and Endothermal Ablation (using heat). It included 43 adults with a faulty great saphenous vein. The goal was to see which treatment better reduced symptoms like heaviness and pain over 3 months.
Phase: PHASE4 • Sponsor: Boston Scientific Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC