New laser shows promise for varicose vein treatment in Head-to-Head trial

NCT ID NCT07603570

Ongoing Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial compares two laser wavelengths (1940 nm vs 1470 nm) for closing off faulty veins in people with symptomatic varicose veins. 220 adults will be randomly assigned to one laser or the other. The main goal is to see which laser achieves complete vein closure at 6 months, with less pain and fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: laser ablation (1940 nm or 1470 nm diode laser)
What this could lead to: If successful, this could show that a newer laser wavelength (1940 nm) works as well or better than the standard one, possibly with less pain and lower energy.
What could go wrong: This is a single-center trial, so results may not apply everywhere. Both lasers are already used; the main question is which is better, not whether the procedure works.

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Conditions

The condition(s) this trial relates to.

varicose disease venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GREAT SAPHENOUS VEIN (GSV) WITH VENOUS REFLUX DISEASE VARICOSE VEINS OF LOWER LIMB

Contacts and locations

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Locations

KSUH

Kafr ash Shaykh, 33516, Egypt

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