Streptococcus pneumoniae discitis

This trial compares two types of knee replacement implants in people aged 75 and older: a standard metal-backed component and a cheaper all-polyethylene (plastic) one. The goal is to see if the all-polyethylene implant performs as well in terms of pain relief, movement, and how l…

This study tests whether a special clot made from a patient's own bone marrow can help spine bones heal together faster and more reliably after spinal fusion surgery. The trial involves 96 adults with degenerative spine disease. Half will receive the standard bone graft, and the …

This study follows 200 people who receive a cementless knee replacement (GMK Sphere) to see how long the implant lasts and how well it works. Participants have severe knee damage from arthritis or other conditions. The goal is to monitor safety and performance in real-world use, …

This Mayo Clinic study tests a new 3D MRI sequence called oZTEo, enhanced with deep learning, to detect bone erosions in the hands of people with inflammatory arthritis. The goal is to see if this advanced scan finds erosions better than standard MRI or X-rays. The study will enr…

This study is tracking 120 people who received a HYPE SCS hip stem during total hip replacement. Researchers will monitor how long the implant lasts, how satisfied patients are, and any complications over 5 years. The goal is to confirm the device is safe and works as intended in…

This study looks at whether helping people with inflammatory arthritis address social needs—like food, housing, or transportation—can reduce missed doctor visits. About 100 adults with conditions like rheumatoid arthritis or lupus who have missed appointments in the past year wil…