Spastic hemiplegia

This study follows 25 people aged 2 to 65 with cerebral palsy or brain damage from lack of oxygen who have already received a new gene therapy given as a nose spray. The therapy delivers 15 genes meant to repair the brain, reduce inflammation, and improve movement and thinking. R…

This trial tests whether adding a robotic glove to mirror therapy can improve arm and hand function in children with hemiparetic cerebral palsy. Participants will receive either robot-assisted or conventional mirror therapy alongside standard neurodevelopmental treatment for six …

This pilot study tests whether a home-based training program using joystick-operated ride-on toys can help children aged 3-8 with hemiplegia improve arm function. Children will use their affected arm to drive the toy through playful challenges, compared to a creative upper extrem…

This study tests whether a mild electrical current applied to the scalp, called transcranial direct current stimulation (tDCS), can enhance motor learning in children with unilateral spastic cerebral palsy. Participants aged 6 to 17 will receive tDCS or a sham during five days of…

This study compares a special exercise program called Coordinative Locomotor Training (CLT) to regular physiotherapy for children aged 8 to 12 with spastic hemiplegic cerebral palsy, a condition that causes stiffness on one side of the body. CLT uses running and skating movements…

This study tests whether augmented reality (AR) games can improve walking and balance in children with cerebral palsy. Forty children will either do exercises wearing AR goggles or receive standard physical therapy. The goal is to see if the AR approach is more effective and enga…

This study tests two different therapies—digital mirror therapy and action observation therapy—to see which better improves arm movement and grip strength in children with hemiplegia (one-sided weakness). Forty-five children aged 6 to 8 will participate. The goal is to find a sim…

This study looks at whether a special exercise method called blood flow restriction training can help children with hemiparetic cerebral palsy (CP) improve their hand grip strength. The method uses a cuff to lightly restrict blood flow during low-intensity exercises, which may bu…

This study looks at the cost and benefits of a two-week day camp for children with mild to moderate arm weakness (hemiparesis) from cerebral palsy or brain injury. In the first week, children wear a constraint on their stronger arm to encourage use of the weaker arm, followed by …

This study tests a dual-task training program for children aged 6-8 with unilateral cerebral palsy. About 70 participants will be split into two groups: one doing balance exercises while also performing fine motor tasks, and the other doing single-task exercises. The goal is to s…

This study looks at whether adding tolperison to botulinum toxin injections helps reduce muscle stiffness and nerve pain in stroke survivors. About 40 adults with spastic hemiplegia (one-sided paralysis) will be followed. Researchers will measure spasticity and walking speed to s…

This study looked at 60 children aged 6 to 10 with hemiplegic cerebral palsy to see which type of balance training works better: playing on a Wii Balance Board or doing reactive balance exercises. Both groups also did standard physical therapy three times a week for eight weeks. …

This pilot study tests whether constraint-induced movement therapy (CIMT) can be effectively delivered via video in the homes of 10 children aged 4-10 with hemiplegic cerebral palsy. The therapy involves encouraging use of the weaker arm while restraining the stronger one. Resear…

This study looks at whether virtual reality games designed for hand-arm training can improve hand function in children with hemiplegic cerebral palsy. Seventeen children will either play VR games or do standard hand exercises for 40 hours over two weeks. Researchers will measure …

This study checks whether a play-based test of arm and hand movements, called the Melbourne Assessment-2, is reliable when done through telehealth for children with hemiplegic cerebral palsy. About 35 children ages 2 to 10 will attend one in-person visit and one telehealth visit,…