Somatoform disorder
MONDO:0003117A category of psychiatric disorders which are characterized by the presence of physical symptoms that suggest a medical condition but are not fully explained by any known medical reasons.
Also known as: somatoform disorder, physiological malfunction arising from mental factor, psychophysiologic disorder, psychosomatic disorder
139 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Could home therapy replace hospital stays for kids with mental health issues?
Disease control OngoingThis study tests whether intensive home-based psychiatric treatment can help children and teens with mental health disorders as an alternative to being in the hospital. Over 3 months, participants receive 3 to 7 home visits per week from a team of doctors, therapists, and other s…
Phase: NA • Sponsor: Medical University Innsbruck • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Dance moves tested as therapy for Brain-Body disorder
Symptom relief OngoingThis study tests whether a structured dance and movement program is practical and acceptable for people with functional neurological disorder (FND), a condition where the brain doesn't send proper signals to the body. Thirty adults with FND will be randomly assigned to either dan…
Phase: NA • Sponsor: King's College London • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Could two weeks of therapy beat six months for anxiety?
Symptom relief OngoingThis study tests whether a short, intensive course of cognitive behavioral therapy (CBT) over 2 weeks works better than the usual weekly sessions over 6 months for people with anxiety disorders. 120 adults with conditions like panic disorder, OCD, or PTSD will be randomly assigne…
Phase: NA • Sponsor: Amsterdam UMC, location VUmc • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can a phone app retrain your tremor?
Symptom relief OngoingThis study tests a smartphone app called Tremor Retrainer for people with functional tremor, a movement disorder not caused by other diseases. About 20 participants aged 10 and older will use the app and be monitored via video. The goal is to see if the app is easy to use and if …
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Can acting out help heal? drama therapy trial targets dual diagnosis
Symptom relief TerminatedThis pilot study tests a specific type of drama therapy for people who have both a mental health condition (like depression or bipolar disorder) and a substance use disorder. Ten participants will attend weekly group drama therapy sessions for 12 weeks, then put on a performance.…
Phase: NA • Sponsor: Boston Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Everyday therapists? study tests Non-Licensed CBT in hospitals
Symptom relief OngoingThis study looks at whether unlicensed professionals can successfully provide cognitive behavioral therapy (CBT) to patients in a general hospital. It includes 250 adults with conditions like anxiety, depression, OCD, and PTSD. The goal is to see if this approach improves psychol…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Can a 'Courage and Love' group therapy beat loneliness in seniors?
Symptom relief OngoingThis study tests a group therapy called Awareness, Courage, and Love (ACL) for older adults with psychiatric disorders who feel lonely. The therapy focuses on mindfulness, sharing feelings, and building connections. Researchers want to see if the program is practical and helpful …
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Shocking the nerve: can a stimulator make pain blocks better?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding a nerve stimulator to standard ultrasound guidance improves the quality of nerve blocks for upper limb surgery. 82 adults having elective arm surgery will be randomly assigned to receive the block with or without the stimulator active. Researchers …
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Virtual reality therapy tested to ease body image woes after bariatric surgery
Symptom relief OngoingThis study tests whether virtual reality sessions with a psychologist can improve body image dissatisfaction in people who had bariatric surgery 18 to 30 months ago. Eleven participants will either receive 10 weekly VR sessions or standard follow-up care. The main goal is to see …
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Digital education aims to ease bigorexia in young Gym-Goers
Symptom relief ENROLLING_BY_INVITATIONThis study tests a 12-week nurse-led digital education program for young men (ages 18-30) who have bigorexia, also known as muscle dysmorphia. Participants must attend a gym and score high on a bigorexia scale. The program aims to improve body image, reduce social anxiety about a…
Phase: NA • Sponsor: Eastern Mediterranean University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Promising tremor device study pulled before it began
Symptom relief TerminatedThis study was designed to see if a biofeedback device called JOGO could help people with functional tremor, a condition where the body shakes uncontrollably. JOGO uses stickers on the skin to read muscle activity and then guides users through training sessions to reduce shaking.…
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Can ketamine ease chronic pain? new study seeks answers
Symptom relief ENROLLING_BY_INVITATIONThis study looks at adults with chronic pain who receive ketamine infusions at Stanford's Pain Management Center. Researchers want to understand which patients improve and what factors predict a good response. The goal is to better tailor this treatment to individuals.
Sponsor: Theresa Lii • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Can a gentle zap to the neck or ear calm body distress?
Symptom relief ENROLLING_BY_INVITATIONThis study compares two non-invasive devices that stimulate the vagus nerve—one placed on the neck, the other on the ear—to see which better reduces physical discomfort and health-related anxiety in people with somatic symptom disorder. Sixty participants will try both devices in…
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Herbal tea may soothe pain and stress in stem cell donors
Symptom relief ENROLLING_BY_INVITATIONThis study is testing whether Jing Si Herbal Tea can reduce pain and anxiety in people donating peripheral blood stem cells. 80 healthy donors aged 20-55 will drink the tea and report their symptoms. The goal is to see if this simple drink can improve the donation experience.
Phase: NA • Sponsor: Buddhist Tzu Chi General Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 18:50 UTC
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New online therapy aims to ease cancer Survivors' fear of recurrence
Symptom relief OngoingThis study tests an online cognitive therapy program, guided by a therapist, to help colorectal cancer survivors who have finished treatment reduce their fear of the cancer returning. The program includes educational text, exercises, and videos. Researchers will compare it to sta…
Phase: NA • Sponsor: Vejle Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 16:50 UTC
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Can peers help people recover from mental illness? new study says maybe
Knowledge-focused OngoingThis study tests a 10-week program called 'Grow to Recovery' for people with mental illness. The program is co-led by a peer (someone who also has a mental illness) and a professional. Researchers want to see if it helps participants feel more hopeful and capable. 138 people are …
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New model aims to speed up rare disease diagnosis
Knowledge-focused OngoingThis study is testing a new way to care for people with rare diseases. It will use advanced genetic testing and a team of specialists to help diagnose patients faster and coordinate their care better. The study involves 136 participants with certain rare diseases and aims to redu…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Magic mushroom compound probes brain in FND patients
Knowledge-focused OngoingThis study looks at how a single dose of psilocybin, the active ingredient in magic mushrooms, affects brain networks in 24 adults with functional neurological disorder (FND). Participants receive the drug with therapeutic support, and brain scans are taken before and after to se…
Phase: NA • Sponsor: King's College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Ottawa study aims to help homeless youth cut back on tobacco and drugs
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at tobacco, cannabis, and other drug use among homeless and at-risk youth in downtown Ottawa. Researchers will follow 520 participants aged 16 and older who are homeless or insecurely housed and have a history of cannabis use and mental illness. The goal is to un…
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Why do people grind their teeth at night? new study seeks answers
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at 50 adults with sleep bruxism (teeth grinding during sleep) to understand how it affects sleep, pain, anxiety, and overall health. Researchers will use sleep tests, blood samples, and questionnaires to find links between bruxism and other conditions. The goal i…
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Stroke mimics: new study follows patients without stroke to uncover hidden patterns
Knowledge-focused OngoingThis study looks at 20 adults who were admitted to a stroke unit with stroke-like symptoms but were found not to have a stroke or other neurological disease. The goal is to describe their thinking and behavior patterns and track their symptoms over 6 months. This research aims to…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Which therapy works best for troubled teens? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 192 teens aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over 9 months. The goal is to…
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Can we predict psychosis? global study seeks answers
Knowledge-focused OngoingThis observational study is collecting data from 2,617 young people (ages 12-30) at clinical high risk for psychosis, plus healthy controls, across 13 countries. Researchers will use clinical assessments, cognitive tests, and biomarkers to build algorithms that predict who will r…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC