Sleep apnea syndrome

This small pilot study tested whether a special oral appliance (like a mouthguard) could reduce episodes of atrial fibrillation, a common heart rhythm problem. Only 3 people participated, and the study was ended early. The device is already used for snoring and sleep apnea, but i…

This study looked at whether using a positive airway pressure (PAP) machine at night can reduce the return of atrial fibrillation (an irregular heartbeat) in people who also have obstructive sleep apnea. About 129 participants with both conditions were assigned to receive either …

This study compared a new prototype nasal mask (Whitsundays) to a standard mask (AirFit N30i) in 30 adults with obstructive sleep apnea. Participants used each mask for 7 nights at home. The goal was to see which mask sealed better, was more comfortable, and easier to use. The st…

This study compared two types of non-invasive breathing support for people with sudden breathing failure who are obese or have sleep apnea. One machine automatically adjusts pressure and volume, while the other uses a fixed pressure setting. The goal was to see which method clear…

This study tested a device that delivers high-flow oxygen through the nose during throat surgery. The goal was to keep patients' oxygen levels safe without using a breathing tube. The trial included 29 adults in two French hospitals. The device was considered safe if blood oxygen…

This study tested a single dose of danavorexton in 41 people with moderate to severe sleep apnea who were having abdominal surgery. The goal was to see if the drug could help them breathe steadily in the recovery room. The trial was terminated early, so results are incomplete.

This study looked at whether using a CPAP machine at night could reduce abnormal acid reflux and lung inflammation in people with idiopathic pulmonary fibrosis (IPF) who also have sleep apnea. Only 7 people enrolled before the study was terminated early. The goal was to measure c…

This study aimed to find early signs of heart and blood vessel damage in people with obstructive sleep apnea, before serious symptoms appear. Researchers planned to follow 133 patients and check if CPAP treatment could reverse these early changes. The study was terminated early, …

This study aimed to see if using a CPAP machine (a device that helps breathing during sleep) reduces inflammation in fat tissue for people with sleep apnea, both obese and non-obese. Researchers planned to compare CPAP treatment to a placebo in 40 men. The study was stopped early…

This study contacted 321 people with sleep apnea who were part of earlier research to see what health problems they had over time. Researchers asked about heart issues, diabetes, cancer, and deaths. They also looked at whether using a CPAP machine affected these outcomes. The goa…

This study involved 65 adults with obstructive sleep apnea who had been using CPAP therapy for at least 6 months. Participants stopped using CPAP for 2 weeks so researchers could measure changes in blood vessel function and nerve control of the heart. The goal was to see if a spe…