Drug induced central sleep apnea
MONDO:0024357A central sleep apnea syndrome induced by medication or substance use. Central sleep apnea is caused by improper signaling from the brainstem to the respiratory muscles and is triggered by either hypoventilation or hyperventilation. Clinical signs include snoring, insomnia or hypersomnia, difficulty concentrating, and fatigue. Recurrent episodes of hypoxia/hypoxemia have long-term detrimental effects on cardiovascular health.
Also known as: drug induced central sleep apnea
37 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could oxygen or a common drug fix Opioid-Linked sleep apnea?
Disease control Recruiting nowThis study investigates whether oxygen and the drug acetazolamide can help stabilize breathing during sleep in people who take prescription opioids and have sleep apnea. Researchers will measure breathing patterns and sleep quality in 150 veterans. The goal is to find new ways to…
Phase: PHASE1, PHASE2 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Could a wearable device replace hospital sleep tests for kids with cerebral palsy?
Diagnosis Recruiting nowThis study is testing whether simple wearable devices can accurately screen for sleep disorders in children with cerebral palsy. About 140 children aged 6 to 15 will wear the devices at home and then undergo a standard hospital sleep test. The goal is to see if the wearable metho…
Phase: NA • Sponsor: University Hospital, Brest • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Simple morning trick may stop sleep apnea device from ruining your bite
Prevention Recruiting nowThis study tests two simple ways to prevent bite changes in people using a mouthpiece for sleep apnea or snoring. Some participants will use a special aligner each morning to gently guide their jaw back into place, while others will do daily jaw exercises. The goal is to see whic…
Phase: NA • Sponsor: Isabel Moreno Hay • Aim: Prevention
Last updated Jun 27, 2026 12:34 UTC
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Could a common drug fix sleep apnea and curb opioid cravings?
Symptom relief Recruiting nowThis study tests whether acetazolamide, a drug used for other types of sleep apnea, can help people on methadone or buprenorphine who develop central sleep apnea. Forty participants will take either the drug or a placebo for 7 days, then have an overnight sleep study. Researchers…
Phase: PHASE2 • Sponsor: Sanjay R Patel • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Medical cannabis under the microscope: 1,000 patients tracked for Real-World relief
Symptom relief Recruiting nowThis study follows 1,000 adults in Canada who are authorized to use medical cannabis for pain, sleep issues, anxiety, depression, or epilepsy. Researchers will track changes in symptoms using standard questionnaires over 24 weeks. The goal is to see how well medical cannabis work…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Can a 4-Week online course tame your night terrors?
Symptom relief Recruiting nowThis study tests a 4-week online course designed to help adults who experience parasomnias—unwanted sleep events like sleep terrors, sleepwalking, and nightmares. The course teaches safety planning, relaxation, and therapy techniques. Researchers will measure whether it reduces h…
Phase: NA • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Memory tricks may help older adults finally get a good Night's sleep
Symptom relief Recruiting nowThis study tests whether a special memory support program can help people aged 50 and older remember and stick to their sleep treatment. The program uses simple memory strategies alongside standard sleep therapy. Researchers will track sleep quality, daily functioning, and life s…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Amino acid supplement tested for better sleep in brain injury
Symptom relief Recruiting nowThis study tests whether taking branched chain amino acids (BCAAs) twice a day for three weeks can improve sleep in people with traumatic brain injury. Researchers will also check if the supplement is easy to take and if participants stick with it. The study involves 300 veterans…
Phase: NA • Sponsor: Portland VA Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Can a simple breath test diagnose diseases in children?
Knowledge-focused Recruiting nowThis study aims to see if analyzing the chemicals in a child's breath can help diagnose and monitor diseases like asthma, neurological disorders, and type 1 diabetes. Researchers will collect breath samples from up to 3,600 children and teens to find patterns linked to these cond…
Sponsor: University Children's Hospital Basel • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New wearable sensor could help kids with breathing issues get better diagnoses
Knowledge-focused Recruiting nowThis study is testing a small, wireless wearable device that tracks breathing in children. It aims to see if the device works well for kids who have trouble with standard sleep or breathing tests, including premature infants, children with sleep apnea, and those with epilepsy at …
Sponsor: NHS Greater Clyde and Glasgow • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New study tests whether a 'Navigator' can speed up sleep apnea care for kids
Knowledge-focused Recruiting nowThis study tests a program called REPOSE, where a patient navigator helps families overcome barriers to getting specialist care for children with sleep-disordered breathing. The navigator provides support, resources, and coordinates care between doctors and parents. The goal is t…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC