Sebaceous gland disorder

This phase II trial is testing whether a combination of talimogene laherparepvec (a modified herpes virus that infects and kills cancer cells) and nivolumab (an immunotherapy drug) can shrink tumors in people with rare skin cancers or lymphomas that haven't responded to standard …

This study is testing whether a new gel applied daily for up to 52 weeks is safe for people with acne. About 400 participants will use the gel on their face and upper body and visit the clinic regularly for checkups. The main goal is to track any side effects, not to measure how …

This study tests a device that uses fractional radiofrequency energy to treat moderate to severe acne. Thirty people aged 18 to 25 will receive the treatment. Researchers will check if acne improves and how satisfied participants are with the results.

This study tests whether a cream called clascoterone (Winlevi) can shrink oil glands and change the oil on the face in people with acne. Ten adults with oily skin and moderate acne will use the cream twice daily for 3 months. Researchers will take small skin samples to see if the…

This study tests a cosmetic cream (RV3278B-OS0386) to see if it can stop acne from returning after a full course of oral isotretinoin. About 102 adults with clear or almost clear skin after isotretinoin will use the cream or a control product twice daily for 12 months. The main g…

This study tests a treatment called photodynamic therapy (PDT) for adults with moderate to severe acne. A gel called Ameluz® is applied to the face, then activated with a special red light. The goal is to see if this combination reduces acne lesions better than a placebo. About 1…

This study tests whether a common antifungal cream, ketoconazole, can treat mild acne as well as a standard retinoid cream, adapalene. Fifty-two people with mild acne will use one of the two creams for 12 weeks. Researchers will count pimples and check for side effects to see if …

This study tests whether an injection made from human fat cells (Tience®) can safely reduce moderate to severe acne scars. Twenty adults aged 18-40 with scars on their cheeks will receive three treatments on one side of the face over three months. Doctors and participants will tr…

This study compares two common acne pills for women: spironolactone (a hormone blocker) and doxycycline (an antibiotic). About 350 women aged 16-40 with moderate to severe acne will take one of the two medicines for several weeks. Researchers will count how many pimples clear up …

This study tests a prescription cream (clascoterone) to treat acne caused by testosterone therapy in transgender men. About 18 participants will use the cream daily for 3 months to see if it reduces pimples without affecting their hormone levels. The goal is to provide a safe acn…

This study follows about 200 people aged 12 and older in Canada who are using a prescription gel containing clindamycin, adapalene, and benzoyl peroxide for acne. Researchers want to see how satisfied patients are, how well they stick to the treatment, and how it affects their qu…

This Phase 3 trial tests a new gel (N-Acetyl-GED-0507-34-LEVO) applied once daily for 12 weeks to reduce acne lesions on the face and trunk. About 400 participants will be randomly assigned to receive either the active gel or a placebo. Researchers will measure changes in lesion …

This Phase 3 trial tests a new gel called N-Acetyl-GED-0507-34-LEVO for acne vulgaris. About 400 people will apply the gel or a placebo daily for 12 weeks. Researchers will count pimples and rate skin clarity to see if the gel works better than placebo.

This study tests whether adding probiotics to the antibiotic azithromycin works better than azithromycin alone for treating mild to moderate acne. Sixty participants with 20 to 50 acne lesions will be treated and their lesion counts measured before and after. The goal is to see i…

This study tests a ginger extract patch for mild to moderate acne in 26 women aged 15–45. Each participant applies the patch to one side of the face after using a standard tretinoin cream, while the other side gets only the cream. Researchers count acne lesions and check skin bac…

This study looks at how the antibiotic doxycycline changes the bacteria on the skin and in the gut of people with acne. Researchers will compare these changes between acne patients and healthy volunteers. The goal is to better understand the link between acne, antibiotics, and th…

This study looks at whether artificial intelligence (AI) can match a dermatologist's diagnosis when a general practitioner sends in photos and questions about a patient's skin condition. Researchers will compare the AI's diagnosis to the dermatologist's for about 1000 adults. The…

This study tracks how consistently 72 adults with acne use their prescribed topical medications. Researchers measure adherence by weighing bottles and using electronic monitors to count doses. The goal is to identify barriers like cost, side effects, or forgetfulness that cause p…

This study brings together 15 expert dermatologists to agree on the best ways to use isotretinoin, a powerful acne medication. The goal is to create clear, practical guidelines on when to prescribe it, how to dose it, and how to monitor side effects. The study does not test a new…