Acne drug showdown: which pill works best for women?
NCT ID NCT04582383
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 26 times
Summary
This study compares two common acne medications—spironolactone (a hormone blocker) and doxycycline (an antibiotic)—in 350 women aged 16 to 40 with moderate to severe acne. The goal is to see which treatment reduces pimples and improves skin appearance more effectively. Participants are randomly assigned to one of the two drugs, and neither they nor their doctors know which they receive.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Arlington Research Center
Arlington, Texas, 76011, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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CCS Texas
Houston, Texas, 77004, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cura Clinical Research
Sherman Oaks, California, 92866, United States
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Cyn3rgy Research
Gresham, Oregon, 97030, United States
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Dawes Fretzin Clinical Research Group
Indianapolis, Indiana, 46250, United States
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Dermatologists of Central States
Cincinnati, Ohio, 45242, United States
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Johnson Dermatology
Fort Smith, Arkansas, 72916, United States
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New Horizon Research Center
Miami, Florida, 33165, United States
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New York University
New York, New York, 10016, United States
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North Texas Center for Clinical Research
Frisco, Texas, 75034, United States
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Northwell Health
North New Hyde Park, New York, 11042, United States
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Ohio State University Medical Center
Columbus, Ohio, 43215, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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University of California San Francisco
San Francisco, California, 94115, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 45209, United States
Conditions
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