Which pill works better for acne? new study compares hormone therapy vs antibiotic
NCT ID NCT04582383
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two common acne pills for women: spironolactone (a hormone blocker) and doxycycline (an antibiotic). About 350 women aged 16-40 with moderate to severe acne will take one of the two medicines for several weeks. Researchers will count how many pimples clear up and check skin improvement to see which treatment works better.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Arlington Research Center
Arlington, Texas, 76011, United States
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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CCS Texas
Houston, Texas, 77004, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cura Clinical Research
Sherman Oaks, California, 92866, United States
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Cyn3rgy Research
Gresham, Oregon, 97030, United States
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Dawes Fretzin Clinical Research Group
Indianapolis, Indiana, 46250, United States
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Dermatologists of Central States
Cincinnati, Ohio, 45242, United States
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Johnson Dermatology
Fort Smith, Arkansas, 72916, United States
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New Horizon Research Center
Miami, Florida, 33165, United States
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New York University
New York, New York, 10016, United States
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North Texas Center for Clinical Research
Frisco, Texas, 75034, United States
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Northwell Health
North New Hyde Park, New York, 11042, United States
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Ohio State University Medical Center
Columbus, Ohio, 43215, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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University of California San Francisco
San Francisco, California, 94115, United States
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University of Miami
Miami, Florida, 33136, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 45209, United States