Antifungal cream could be new acne treatment

NCT ID NCT07237763

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a common antifungal cream, ketoconazole, can treat mild acne as well as a standard retinoid cream, adapalene. Fifty-two people with mild acne will use one of the two creams for 12 weeks. Researchers will count pimples and check for side effects to see if ketoconazole is a good alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ketoconazole 2% cream
What this could lead to
If ketoconazole works as well as adapalene with fewer side effects, it could offer a gentler option for treating mild acne.
What could go wrong
This is a small, early-stage trial with only 52 people, so results may not apply to everyone. Ketoconazole is an antifungal, not a standard acne treatment, so it may not be effective for all acne types.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cairo university

    Cairo, Egypt

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