Acne cream aims to shrink oil glands in new study

NCT ID NCT06425900

First seen Nov 05, 2025 · Last updated Jun 21, 2026 · Updated 32 times

Summary

This study tests whether a cream called clascoterone (Winlevi) can shrink oil glands and change the oil on the face in people with acne. Ten adults with oily skin and moderate acne will use the cream twice daily for 3 months. Researchers will take small skin samples to see if the glands get smaller and if the oil's makeup changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dermatology Consulting Services, PLLC

    High Point, North Carolina, 27262, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

clascoterone cream 1%

What this could lead to

If it works, this could point toward a treatment that reduces acne by shrinking oil glands and changing oil composition.

What could go wrong

This is a very small early-phase trial with only 10 participants, so results may not apply to everyone. It also requires ongoing cream use, not a one-time fix.

Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.