Respiratory paralysis
MONDO:0043775Complete or severe weakness of the muscles of respiration. This condition may be associated with motor neuron diseases; peripheral nerve diseases; neuromuscular junction diseases; spinal cord diseases; injury to the phrenic nerve; and other disorders.
Also known as: paralysis of diaphragm, diaphragmatic paralysis, muscle paralysis, respiratory, muscle paralyzes, respiratory, paralysis, diaphragmatic, paralysis, respiratory, paralysis, respiratory muscle, respiratory muscle paralysis
94 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Simple stretch may speed diaphragm recovery after heart surgery
Disease control CompletedThis study investigates whether adding a contract-relax physical therapy technique to standard respiratory care can improve diaphragm function in patients who develop diaphragmatic paresis after cardiac surgery. The trial enrolls adults who have undergone heart surgery with a hea…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Ultrafast ultrasound may offer quicker diagnosis for diaphragm dysfunction
Diagnosis CompletedThis study explores whether ultrafast ultrasound can accurately assess diaphragm function in adults with known or suspected diaphragm dysfunction. Researchers will compare ultrasound measurements with standard tests like pressure measurements and electrical signals from the diaph…
Phase: NA • Sponsor: Institut de Myologie, France • Aim: Diagnosis
Last updated Jul 01, 2026 00:00 UTC
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Could a simple breath test spot hidden diseases early?
Diagnosis CompletedThis study is testing a portable, non-invasive breath analyzer that measures tiny particles in exhaled breath to screen for conditions like type 2 diabetes, liver disease, kidney disease, and lung disease. Researchers will enroll healthy volunteers and people with known diagnoses…
Sponsor: Respyr • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New scale could help predict fall risk for hospital patients in turkey
Diagnosis CompletedThis study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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Radiation-Free lung scans for kids? new MRI shows promise
Diagnosis CompletedThis study tested a new MRI technique that can take pictures of children's lungs without using radiation or injecting contrast dye. 72 children aged 6-16 had both a standard CT scan and this new MRI. The goal was to see if the MRI could produce clear images of the lungs, potentia…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 26, 2026 15:40 UTC
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Less numbing medicine may keep diaphragm working during shoulder surgery
Symptom relief CompletedThis study tested whether using a smaller amount of a weaker numbing medicine (ropivacaine) during a shoulder nerve block could reduce the risk of temporary diaphragm paralysis. 60 adults having shoulder surgery took part. The goal was to see if the low-dose approach could still …
Phase: PHASE3 • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New hope for preventing Post-Surgery confusion in seniors
Symptom relief CompletedThis study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…
Phase: EARLY_PHASE1 • Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Ice your pain away: nerve freezing may cut opioid use after lung surgery
Symptom relief CompletedThis study tested freezing the nerves between the ribs during robot-assisted lung surgery to see if it reduces pain and the need for painkillers afterward. 33 adults having lung surgery were randomly assigned to get the nerve freeze or standard pain medicine. Researchers tracked …
Phase: PHASE4 • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Shoulder surgery pain study: which nerve block works best?
Symptom relief CompletedThis study tested two methods of numbing the suprascapular nerve (a nerve in the shoulder) to control pain after arthroscopic shoulder surgery. Sixty adults scheduled for shoulder surgery received either an anterior or posterior nerve block. Researchers measured pain levels, diap…
Phase: NA • Sponsor: Istanbul Medeniyet University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Breathing training offers hope for COVID Long-Haulers with weak diaphragms
Symptom relief CompletedThis study looked at whether 6 weeks of special breathing exercises (inspiratory muscle training) can improve diaphragm strength and reduce shortness of breath in 18 COVID-19 survivors who still had trouble breathing. Participants had proven diaphragm weakness and no other explan…
Phase: NA • Sponsor: RWTH Aachen University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Physiotherapy students test muscle relief techniques on themselves
Symptom relief CompletedThis study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New nerve block combo may spare breathing while killing shoulder pain
Symptom relief CompletedThis study tested two ways to numb the shoulder after surgery: the standard interscalene block and a combination of two other blocks (infraclavicular and anterior suprascapular). The goal was to see if the combination could provide equal pain relief without causing temporary diap…
Phase: NA • Sponsor: University of Chile • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Can a computer speed up breathing recovery in kids?
Symptom relief CompletedThis study tested whether a computer-driven system called Smartcare/PS could help children with respiratory failure come off a breathing machine faster than usual care. Thirty children were enrolled, and the system automatically adjusted breathing support based on each child's ne…
Phase: NA • Sponsor: St. Justine's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Who should control your sedation during surgery? new study compares options
Symptom relief CompletedThis study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Patients take control: Self-Sedation may ease anxiety in the ICU
Symptom relief CompletedThis study tested whether critically ill patients on breathing machines could safely manage their own sedation using a button-controlled device. 161 adults in the ICU were randomly assigned to either self-manage their sedation or have it managed by a nurse. The goal was to see if…
Phase: PHASE2, PHASE3 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New turkish health survey could improve care for muscle and joint problems
Knowledge-focused CompletedThis study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…
Sponsor: Istanbul Bilgi University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Scientists examine lung cells to understand chronic lung disease
Knowledge-focused CompletedThis study looked at immune cells called alveolar macrophages in the lungs of 18 people with non-infectious lung diseases. Researchers used a technique called flow cytometry to study the surface proteins on these cells. The goal was to better understand the role of these cells in…
Sponsor: Rennes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Shoulder block study checks for breathing side effects
Knowledge-focused CompletedThis study observed 61 adults having shoulder surgery to see how a specific combination of nerve blocks affects the diaphragm, the main muscle for breathing. Researchers used ultrasound to measure diaphragm movement before and after the block. The goal was to find out if this tec…
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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What's it like to live with a home breathing machine? new study asks patients and families
Knowledge-focused CompletedThis study looked at the experiences of 126 people in Denmark who rely on a breathing machine at home, along with their families and the trained caregivers who help them. The goal was to understand the challenges and successes of this life-sustaining care. No new treatments were …
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Could a stroll beat a sprint for oxygen testing?
Knowledge-focused CompletedThis study looked at 93 people with lung disease who get short of breath when active. Participants did two 6-minute walk tests: one at their fastest pace and one at their normal walking speed. The goal was to see if the normal-speed test gives a more accurate picture of when they…
Phase: NA • Sponsor: Hampshire Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Heart surgery patients: one in six may face hidden diaphragm trouble
Knowledge-focused CompletedThis study tracked 157 heart surgery patients to see how many still have a weak diaphragm 7 days after their operation. Using ultrasound, researchers measured diaphragm movement during breathing and sniffing. The goal is to understand how common persistent diaphragm problems are …
Sponsor: CMC Ambroise Paré • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Physios take on ER duty: study tests if they can replace doctors for back pain
Knowledge-focused CompletedThis study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Which ventilator mode is best? new study aims to find out
Knowledge-focused CompletedThis pilot study tested three common ventilator modes—volume control, pressure control, and adaptive pressure control—in 566 ICU adults with respiratory failure. The goal was to see which mode leads to more days alive and off the ventilator. The study is a first step to guide fut…
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Oxford researchers seek better way to open collapsed lungs in ICU
Knowledge-focused CompletedThis University of Oxford study looked at 48 ICU patients on ventilators for respiratory failure. Doctors sometimes inflate the lungs briefly (a recruitment manoeuvre) to reopen collapsed areas, but it's unclear when this helps. Researchers used a device to measure lung volume an…
Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Which arm block spares the diaphragm? new study pits two techniques Head-to-Head
Knowledge-focused CompletedThis study compared two ultrasound-guided nerve block techniques for hand, wrist, or forearm surgery to see which one causes less temporary diaphragm paralysis. 91 adults were randomly assigned to receive either a costoclavicular or lateral sagittal infraclavicular block. The goa…
Phase: NA • Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Brain waves may predict ventilator weaning success
Knowledge-focused CompletedThis study looked at whether measuring tiny brain signals during a breathing test can help predict if a patient on a ventilator will successfully breathe on their own. Researchers monitored 70 intubated adults as they tried breathing without the machine. The goal is to find a sim…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Hospital dietitians boost nutrition in lung patients, study finds
Knowledge-focused CompletedThis study tested whether having a dietitian help patients with lung disease order meals during a hospital stay could improve their nutrition and reduce the chance of being readmitted after discharge. 41 patients at nutritional risk took part. Researchers measured daily food inta…
Sponsor: Gødstrup Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Mind, spirit, and pain: new study explores what chronic pain patients really believe
Knowledge-focused CompletedThis study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Small study tests best ventilator settings for ICU breathing measurements
Knowledge-focused CompletedThis study looked at 24 critically ill patients on breathing machines to see how changing the machine's settings affects measurements of breathing effort. Researchers compared a simple bedside measurement with a more invasive gold-standard technique. The goal was to find the best…
Phase: NA • Sponsor: Fondazione IRCCS San Gerardo dei Tintori • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:16 UTC