Paroxysmal familial ventricular fibrillation

This trial tests a special implantable cardioverter-defibrillator (ICD) that uses a single lead to sense both heart chambers, aiming to detect atrial fibrillation and other arrhythmias early. It includes 56 people who need a single-chamber ICD and are in normal sinus rhythm at th…

This study compared two hormone protocols for women with high ovarian response undergoing IVF. One used progesterone (dydrogesterone) and the other used a GnRH antagonist. The goal was to see which approach leads to more eggs retrieved and higher pregnancy rates. 200 women partic…

This study tested whether taking an oral progesterone pill (Seidigestan) can prevent early ovulation during IVF as well as the standard daily injections (Astarté). 150 healthy egg donors participated. If the pill works just as well, it could make IVF more convenient and less pain…

This study looked at whether giving a higher dose of vaginal progesterone (800 mg vs 1200 mg daily) can improve pregnancy rates in women with low progesterone levels on the day of embryo transfer. It involved 87 women undergoing a single frozen embryo transfer. The goal was to se…

This study tested a ready-to-use calcium ionophore medium (GM508 CultActive) on eggs from 68 IVF patients who had low fertilization rates, poor embryo quality, or were over 40. The medium was applied shortly after sperm injection to try to improve fertilization and embryo develop…

This study tested whether permanent pacemakers can be safely implanted using only ultrasound (transthoracic echocardiography) instead of traditional X-ray guidance. Thirty-one adults with arrhythmias who needed a pacemaker took part. The goal was to see if the procedure could be …

This study tested a new type of wire (lead) for implantable heart devices that deliver shocks to stop dangerous fast heart rhythms. Researchers checked how safe and effective the lead was in 998 people who needed a defibrillator or heart failure device. The lead was placed in a s…

This study tested a high dose of a fertility drug called follitropin delta, mixed with another hormone (hCG), in 118 women undergoing IVF. The goal was to see if this combination could improve the number of good-quality embryos. The study was completed and focused on women aged 1…

This study looked at whether a three-month diet and exercise program before IVF could improve live birth rates in overweight and obese women. 197 women were randomly assigned to either the weight loss group or a control group. The goal was to see if losing weight beforehand leads…

This trial tests whether a wearable patch called MEMO Patch V2 can detect heart rhythm disorders (arrhythmias) more effectively than the standard 24-hour Holter monitor. Adults with symptoms like palpitations or dizziness, or those who have had a stroke of unknown cause, will wea…

This study investigates whether an Apple Watch can accurately detect heart rhythm problems (arrhythmias) in children aged 6 to 21 who are already scheduled for standard heart monitoring. Researchers will compare the watch's ECG and heart rate readings to those from conventional c…

This study tested a new non-invasive tool called ECG-Imaging that uses many electrodes on the body to create a 3D map of the heart's electrical activity. The goal was to see if it can more accurately locate the source of heart rhythm problems compared to a standard ECG. 362 parti…

This study looked at whether a 12-week virtual exercise program could help women with cardiac implantable electronic devices (CIEDs) improve their physical fitness, quality of life, and mental health. Twenty women took part, doing either high-intensity interval training (HIIT) or…

This study aims to establish national reference levels for radiation exposure during X-ray guided procedures to correct heart rhythm disorders, such as pacemaker insertions and ablations. Researchers will collect radiation dose data from over 4,000 adult patients undergoing these…

This study tests whether wearing a heart monitor for 14 days can detect dangerous heart rhythms in people with mitral valve prolapse (a common heart valve condition) better than the usual 24-hour test. About 60 adults with MVP will wear a patch monitor for two weeks. The goal is …

This study looked at whether a special mapping tool called vMap can help doctors perform heart ablations more efficiently for people with irregular heartbeats (arrhythmias). Researchers tracked 112 patients to see if using vMap reduced procedure time and improved success rates. T…

This study looked at 300 women undergoing frozen embryo transfer as part of IVF treatment. Researchers measured progesterone levels in the blood to understand how the body processes the hormone. The goal was to find out if low progesterone on transfer day leads to higher failure …

This completed registry study followed over 5,000 people with heart rhythm disorders who received Abbott devices during standard procedures. The goal was to collect real-world data on safety and how well the devices work. No new treatments were tested; instead, the study observed…

This completed study looked at how the heart medication amiodarone behaves in children aged 0 to 18 with heart rhythm disorders. Researchers took blood samples from 57 children to measure drug levels and understand how the body processes it. The goal was to find the best dose for…

This study used a special brain imaging technique called near-infrared spectroscopy to see how the brain responds to pain and sounds while people are under general anesthesia. 44 healthy volunteers aged 12-30 were given either a painkiller (remifentanil) or a placebo. The goal wa…

This study followed 214 children born from two different fertility treatments—CAPA-IVM and conventional IVF—to see if their development and behavior at age 5 were similar. Researchers used parent questionnaires to assess communication, motor skills, problem-solving, and emotional…

This study looked at 87 women who had no eggs retrieved during their first IVF cycle. Researchers wanted to see if a second round of ovulation-inducing medication could lead to successful egg retrieval. The goal was to understand which factors might predict failure and how to imp…