IVF pill could replace daily shots, study finds

NCT ID NCT05954962

Completed Disease control Sponsor: Instituto Bernabeu Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking an oral progesterone pill (Seidigestan) can prevent early ovulation during IVF as well as the standard daily injections (Astarté). 150 healthy egg donors participated. If the pill works just as well, it could make IVF more convenient and less painful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: micronized natural progesterone (Seidigestan) and ganirelix acetate (Astarté)
What this could lead to: If successful, this could offer a simpler, pill-based alternative to daily injections for preventing early ovulation during IVF.
What could go wrong: This is a small, completed Phase 4 trial in healthy egg donors. Results may not apply to all IVF patients, and oral progesterone may be less effective in some cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ventricular fibrillation, paroxysmal familial, type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IVF

Contacts and locations

Locations

Instituto Bernabeu

Elche, Alicante, 03206, Spain

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