Can a blood injection reboot ovaries? small trial tests PRP for fertility

NCT ID NCT04381299

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a woman's own platelet-rich plasma (PRP) into the ovary can help restore function in women with premature ovarian insufficiency (early menopause). 35 women under 40 will receive PRP in one ovary and a saline placebo in the other. The main goal is to see if new follicles grow and produce estrogen within 12 weeks. This is an early, small trial, so results are uncertain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

autologous platelet rich plasma

What this could lead to

If it works, this could offer a way to restore ovarian function and improve fertility chances for women with premature ovarian failure.

What could go wrong

This is a very small, early trial with only 35 participants. The treatment may not work, and any benefit could be due to the placebo effect from the saline injection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infertility disorder premature menopause primary ovarian failure ventricular fibrillation, paroxysmal familial, type 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ART Fertility Clinics LLC

    Abu Dhabi, Abu Dhabi Emirate, 60202, United Arab Emirates