Premature menopause
MONDO:0001119Cessation of menstruation before the age of 40. Symptoms include hot flashes, night sweats, mood swings, and decreased sex drive.
Also known as: POF, early menopause, premature menopause, premature ovarian failure
21 clinical trials for this condition and its sub-types.
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Could a simple blood injection reverse early menopause?
Disease control Recruiting nowThis trial investigates whether injecting a woman's own platelet-rich plasma (PRP) into her ovaries can restart menstrual cycles and improve hormone levels. It includes 100 women under 40 with premature ovarian failure (early menopause). Participants receive either PRP or a place…
Phase: PHASE2, PHASE3 • Sponsor: Genesis Athens Clinic • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New program aims to ease menopause for young cancer survivors
Symptom relief Recruiting nowThis study is creating and testing a nurse-led program for women who experience early menopause after cancer. The program includes personalized education, decision support, and skills to manage menopause symptoms. About 117 women who have completed cancer treatment will take part…
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Hormone implants could ease menopause symptoms for years
Symptom relief Recruiting nowThis study tests small hormone implants placed under the skin to relieve menopause symptoms like hot flashes, low mood, and sexual problems. It includes 140 women with natural menopause, early ovarian failure, or menopause from cervical cancer treatment. Researchers will check ho…
Phase: PHASE3 • Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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New study explores hidden health risks after ovary removal
Knowledge-focused Recruiting nowThis study follows 120 women aged 35-50 who are having their ovaries removed (oophorectomy) for non-cancer reasons. Researchers will track changes in quality of life, heart health, brain function, and body fat over one year. Some women may start hormone therapy as part of routine…
Sponsor: University of Jyvaskyla • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Early menopause linked to blood pressure problems? new study investigates
Knowledge-focused Recruiting nowThis study looks at how early menopause (before age 45) affects the nerves that control blood pressure. Researchers will measure nerve activity and blood pressure in 160 women aged 35-70. The goal is to understand why these women may have higher blood pressure and find ways to he…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC